SCHEMBL4137685

SCHEMBL4137685

NC(CO)CCC(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
MAPK1 P28482 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
SLC15A1 P46059 2/20 0.47
LTA4H P09960 1/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
HPGD P15428 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
LMNA P02545 1/20 0.45
CDC25B P30305 1/20 0.44
SLC1A3 P43003 3/20 0.43
SLC1A1 P43005 3/20 0.43
SLC1A2 P43004 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8146945 1.00 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1SLC15A1LTA4H
SCHEMBL22273540 0.92 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
SCHEMBL30578035 0.86 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1SLC15A1LTA4H
SCHEMBL27698377 0.86 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
SCHEMBL8844071 0.86 ALDH1A1 (0.51) ALDH1A1MAPK1L3MBTL1SLC15A1LTA4H
SCHEMBL8435134 0.85 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
SCHEMBL21919739 0.85 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
SCHEMBL21319262 0.85 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1SLC15A1KMT2A
SCHEMBL20364073 0.84 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1SLC15A1LTA4H
SCHEMBL6822910 0.84 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1SLC15A1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4072530-B1 STIMULI - OR BIO- RESPONSIVE COPOLYMERS, THE POLYMERSOMES COMPRISING THE SAME AND THEIR USE IN DRUG DELIVERY CENTRE NAT RECH SCIENT (FR) 2023-08-30 EP disclosed
WO-2021116331-A1 STIMULI - OR BIO- RESPONSIVE COPOLYMERS, THE POLYMERSOMES COMPRISING THE SAME AND THEIR USE IN DRUG DELIVERY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-06-17 WO disclosed
US-8957205-B2 Cycloalkane carboxamide derivatives and production process of same SEIKAGAKU CORPORATION (JP) 2015-02-17 US disclosed
CN-101370773-B Cycloalkanecarboxamide derivative and method for producing same SEIKAGAKU KOGYO CO LTD 2014-04-09 CN disclosed
US-20090156805-A1 Cycloalkane Carboxamide Derivatives and Production Process of Same SEIKAGAKU CORPORATION (JP) 2009-06-18 US disclosed
CN-101370773-A Cycloalkanecarboxamide derivative and method for producing same SEIKAGAKU KOGYO CO LTD (JP) 2009-02-18 CN disclosed
EP-1972615-A1 CYCLOALKANECARBOXAMIDE DERIVATIVE AND METHOD FOR PRODUCING SAME SEIKAGAKU CORPORATION (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156805-A1 Cycloalkane Carboxamide Derivatives and Production Process of Same CTSK, CTSS, CTSB ALDH1A1 1899/4885MAPK1 1482/4885L3MBTL1 4637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.