Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977022 | 0.69 | MEN1 (0.31) | MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL14713012 | 0.64 | ENPP3 (0.43) | MEN1KMT2ARXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11147247 | 0.64 | MEN1 (0.42) | MEN1KMT2ARXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL21104341 | 0.63 | MEN1 (0.47) | MEN1KMT2ARXFP1ALDH1A1SMN1; SMN2 | |
| Butane SCHEMBL9547559 | 0.62 | LMNA (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12758213 | 0.62 | LMNA (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL12609622 | 0.62 | KMT2A (0.50) | MEN1KMT2ARXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12609668 | 0.62 | MEN1 (0.50) | MEN1KMT2ARXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14020128 | 0.62 | MEN1 (0.46) | MEN1KMT2ARXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12609730 | 0.61 | MEN1 (0.49) | MEN1KMT2ARXFP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688896-A | Non-linear optically active polycarbonate | AKZO NOBEL N.V. (NL) | 1997-11-18 | — | — | US | disclosed |
| US-5588083-A | Non-linear optically active polycarbonate | AKZO NOBEL N.V. (NL) | 1996-12-24 | — | — | US | disclosed |