Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811566 | 0.80 | GRM8 (0.44) | MAPTABCC4LMNAALKBH5SUCNR1 | |
| SCHEMBL8531618 | 0.77 | LMNA (0.50) | LMNAALKBH5SUCNR1EGLN1TSHR | |
| SCHEMBL3478449 | 0.76 | LMNA (0.42) | MAPTABCC4LMNATSHRBLM | |
| SCHEMBL8965148 | 0.73 | TSHR (0.33) | MAPTTSHRALDH1A1 | |
| SCHEMBL5141700 | 0.72 | PKM (0.36) | MAPTABCC4SMN1; SMN2PKM | |
| SCHEMBL5363512 | 0.72 | ABCC4 (0.36) | MAPTABCC4TSHRNFKB1SLC6A2 | |
| SCHEMBL17733001 | 0.71 | LMNA (0.38) | LMNAALKBH5SUCNR1EGLN1TSHR | |
| SCHEMBL247134 | 0.71 | — | — | |
| SCHEMBL3435804 | 0.70 | TSHR (0.30) | TSHR | |
| SCHEMBL8844590 | 0.69 | FFAR3 (0.46) | LMNAALKBH5SUCNR1EGLN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679849-A | Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide and a derivative thereof | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| US-4150242-A | OXIDATION, HYDROLYSIS, ACIDIFICATION | MONSANTO COMPANY (US) | 1979-04-17 | — | — | US | claimed |
| US-4149014-A | Process for the preparation of bis-(β-carboxyethyl)alkyl phosphine oxides from tris-cyanoethyl phosphine | MONSANTO COMPANY (US) | 1979-04-10 | — | — | US | claimed |
| US-5679849-A | Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide and a derivative thereof | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| US-5679849-A | Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide and a derivative thereof | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| US-5679849-A | Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide and a derivative thereof | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0156139-A2 | Bis(beta-carboxyethyl)isobutyl, sec. butyl and T-butyl Phosphine oxide and polyamides containing the same | AMERICAN CYANAMID COMPANY (US) | 1985-10-02 | — | — | EP | disclosed |
| US-4537993-A | Bis(β-carboxyethyl)isobutyl, sec. butyl and t-butyl phosphine oxide and polyamides containing the same | AMERICAN CYANAMID COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| US-4150242-A | OXIDATION, HYDROLYSIS, ACIDIFICATION | MONSANTO COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-4150242-A | OXIDATION, HYDROLYSIS, ACIDIFICATION | MONSANTO COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-4150242-A | OXIDATION, HYDROLYSIS, ACIDIFICATION | MONSANTO COMPANY (US) | 1979-04-17 | — | — | US | disclosed |
| US-4149014-A | Process for the preparation of bis-(β-carboxyethyl)alkyl phosphine oxides from tris-cyanoethyl phosphine | MONSANTO COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4149014-A | Process for the preparation of bis-(β-carboxyethyl)alkyl phosphine oxides from tris-cyanoethyl phosphine | MONSANTO COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4149014-A | Process for the preparation of bis-(β-carboxyethyl)alkyl phosphine oxides from tris-cyanoethyl phosphine | MONSANTO COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4092302-A | PERMANENT ANTISTATIC, MOISTURE TRANSPORT AND MOISTURE REGAIN, AND FLAME-RESISTANT PROPERTIES | MONSANTO COMPANY (US) | 1978-05-30 | — | — | US | disclosed |
| US-4071549-A | Process for the preparation of bis-(beta-cyanoethyl) alkyl phosphine from tris-cyanoethyl phosphine | MONSANTO COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-4032517-A | ADIPIC ACID, HEXAMETHYLENEDIAMINE, BIS(B-CARBOXYETHYL)-ALKYLPHOSPHINE OXIDE | MONSANTO COMPANY (US) | 1977-06-28 | — | — | US | disclosed |