Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.47 |
| ▸ | ARG2 | P78540 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1504428 | 0.85 | ARG1 (0.50) | ARG1ARG2GGT1KDM4CMEN1 | |
| SCHEMBL1455221 | 0.85 | ARG1 (0.50) | ARG1ARG2GGT1KDM4CMEN1 | |
| SCHEMBL20978268 | 0.85 | ARG1 (0.50) | ARG1ARG2GGT1KDM4CMEN1 | |
| SCHEMBL161929 | 0.82 | ARG1 (0.47) | ARG1ARG2GGT1KDM4CMEN1 | |
| SCHEMBL202490 | 0.82 | ARG1 (0.47) | ARG1ARG2GGT1KDM4CMEN1 | |
| SCHEMBL6431682 | 0.82 | ARG1 (0.47) | ARG1ARG2GGT1KDM4CMEN1 | |
| Hydrochloric Acid SCHEMBL11674300 | 0.81 | ARG1 (0.46) | ARG1ARG2GGT1KDM4CMEN1 | |
| Hydrochloric Acid SCHEMBL11674295 | 0.81 | ARG1 (0.46) | ARG1ARG2GGT1KDM4CMEN1 | |
| SCHEMBL31370370 | 0.80 | ARG1 (0.53) | ARG1ARG2GGT1KDM4CMEN1 | |
| SCHEMBL28429572 | 0.80 | ARG1 (0.53) | ARG1ARG2GGT1KDM4CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663364-A | Heme binding compounds and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0707577-A4 | HEME BINDING COMPOUNDS AND USE THEREOF | WISCONSIN MED COLLEGE INC (US) | 1996-11-06 | — | — | EP | disclosed |
| EP-0707577-A1 | HEME BINDING COMPOUNDS AND USE THEREOF | MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1996-04-24 | — | — | EP | disclosed |
| US-5464858-A | Heme binding compounds and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5424447-A | Heme binding compounds and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1995001972-A1 | HEME BINDING COMPOUNDS AND USE THEREOF | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-01-19 | — | — | WO | disclosed |