Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800490 | 0.82 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL1504409 | 0.82 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL28729833 | 0.82 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL4586895 | 0.82 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL10667207 | 0.82 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL9233627 | 0.76 | SLC7A5 (0.46) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL10620084 | 0.73 | MEN1 (0.46) | SLC7A5SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL5322808 | 0.71 | SLC7A5 (0.58) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL6663362 | 0.71 | SLC7A5 (0.58) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL6919538 | 0.70 | DPP4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663364-A | Heme binding compounds and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0707577-A4 | HEME BINDING COMPOUNDS AND USE THEREOF | WISCONSIN MED COLLEGE INC (US) | 1996-11-06 | — | — | EP | disclosed |
| EP-0707577-A1 | HEME BINDING COMPOUNDS AND USE THEREOF | MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1996-04-24 | — | — | EP | disclosed |
| US-5464858-A | Heme binding compounds and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5424447-A | Heme binding compounds and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1995001972-A1 | HEME BINDING COMPOUNDS AND USE THEREOF | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-01-19 | — | — | WO | disclosed |