Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586895 | 1.00 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL1504409 | 1.00 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL28729833 | 1.00 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL10667207 | 1.00 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL20198745 | 0.86 | SLC7A5 (0.31) | SLC7A5 | |
| SCHEMBL9233627 | 0.83 | SLC7A5 (0.46) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL8845182 | 0.82 | SLC7A5 (0.48) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL27644223 | 0.81 | SLC7A5 (0.42) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL27644228 | 0.81 | SLC7A5 (0.42) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL393844 | 0.81 | GFPT1 (0.46) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230037-B1 | CYTOPROTECTIVE DERIVATIVES USEFUL IN ISCHEMIC DISEASES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | ITALFARMACO S.p.A. (IT) | 1991-03-06 | — | — | EP | disclosed |
| US-4789681-A | CARDIOPROTECTIVE AGENTS | ITALFARMACO S.P.A. (IT) | 1988-12-06 | — | — | US | disclosed |
| EP-0230037-A1 | Cytoprotective derivatives useful in ischemic diseases, their preparation and compositions containing them | ITALFARMACO S.p.A. (IT) | 1987-07-29 | — | — | EP | disclosed |