Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 17/20 | 0.76 |
| ▸ | GABRG2 | P18507 | 17/20 | 0.76 |
| ▸ | GABRB3 | P28472 | 17/20 | 0.76 |
| ▸ | GABRA5 | P31644 | 17/20 | 0.76 |
| ▸ | GABRA3 | P34903 | 17/20 | 0.76 |
| ▸ | GABRA2 | P47869 | 15/20 | 0.76 |
| ▸ | GABRB2 | P47870 | 11/20 | 0.76 |
| ▸ | GABRA6 | Q16445 | 11/20 | 0.76 |
| ▸ | GABRP | O00591 | 10/20 | 0.76 |
| ▸ | GABRD | O14764 | 10/20 | 0.76 |
| ▸ | GABRB1 | P18505 | 10/20 | 0.76 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.76 |
| ▸ | GABRE | P78334 | 10/20 | 0.76 |
| ▸ | GABRG1 | Q8N1C3 | 10/20 | 0.76 |
| ▸ | GABRG3 | Q99928 | 10/20 | 0.76 |
| ▸ | GABRQ | Q9UN88 | 10/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494399 | 0.90 | GABRA1 (0.64) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9075672 | 0.90 | GABRA1 (0.70) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8176103 | 0.90 | GABRA1 (0.70) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9073976 | 0.87 | GABRA1 (0.75) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9075578 | 0.87 | GABRA1 (0.67) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6224370 | 0.87 | GABRA1 (0.74) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9075977 | 0.86 | GABRA1 (0.66) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9076649 | 0.86 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9584162 | 0.86 | GABRA1 (0.74) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10390445 | 0.86 | GABRA1 (0.74) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700808-A | TREATING SLEEP DISTURBANCE, EPILEPSY | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-23 | — | — | US | disclosed |
| US-5414002-A | Anxiolytic agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| US-5254563-A | Bioavailability; central nervous system disorders | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-10-19 | — | — | US | disclosed |