Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 18/20 | 0.70 |
| ▸ | GABRG2 | P18507 | 18/20 | 0.70 |
| ▸ | GABRB3 | P28472 | 18/20 | 0.70 |
| ▸ | GABRA5 | P31644 | 18/20 | 0.70 |
| ▸ | GABRA3 | P34903 | 18/20 | 0.70 |
| ▸ | GABRA2 | P47869 | 16/20 | 0.70 |
| ▸ | GABRA6 | Q16445 | 11/20 | 0.70 |
| ▸ | GABRA4 | P48169 | 10/20 | 0.70 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.70 |
| ▸ | GABRP | O00591 | 9/20 | 0.70 |
| ▸ | GABRD | O14764 | 9/20 | 0.70 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.70 |
| ▸ | GABRE | P78334 | 9/20 | 0.70 |
| ▸ | GABRG1 | Q8N1C3 | 9/20 | 0.70 |
| ▸ | GABRG3 | Q99928 | 9/20 | 0.70 |
| ▸ | GABRQ | Q9UN88 | 9/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845288 | 0.90 | GABRA1 (0.76) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8176103 | 0.88 | GABRA1 (0.70) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10708438 | 0.87 | GABRA1 (0.81) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9073976 | 0.85 | GABRA1 (0.75) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9075578 | 0.85 | GABRA1 (0.67) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6224370 | 0.85 | GABRA1 (0.74) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10390445 | 0.84 | GABRA1 (0.74) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9075977 | 0.84 | GABRA1 (0.66) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9076649 | 0.84 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9584162 | 0.84 | GABRA1 (0.74) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506234-A | PSYCHOPHARMACEUTICAL AGENTS WHICH BIND TO BENZODIAZEPINE RECEPTORS; ANXIOLYTIC AGENTS; MINIMAL SIDE EFFECTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-04-09 | — | — | US | disclosed |