Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473142 | 0.76 | CA12 (0.36) | ALDH1A1TSHR | |
| SCHEMBL12932625 | 0.71 | AOC3 (0.44) | AOC3 | |
| SCHEMBL30515013 | 0.70 | CYP3A4 (0.56) | MAOBCYP3A4TP53ALDH1A1TSHR | |
| SCHEMBL30515092 | 0.70 | CYP3A4 (0.56) | MAOBCYP3A4TP53ALDH1A1TSHR | |
| SCHEMBL25336536 | 0.70 | CYP3A4 (0.56) | MAOBCYP3A4TP53ALDH1A1TSHR | |
| SCHEMBL25320768 | 0.70 | CYP3A4 (0.56) | MAOBCYP3A4TP53ALDH1A1TSHR | |
| SCHEMBL25320764 | 0.70 | CYP3A4 (0.56) | MAOBCYP3A4TP53ALDH1A1TSHR | |
| SCHEMBL11827528 | 0.69 | POLB (0.50) | MTNR1AMTNR1B | |
| SCHEMBL112113 | 0.69 | CYP3A4 (0.63) | MAOBCYP3A4TP53ALDH1A1TSHR | |
| SCHEMBL17171595 | 0.68 | LMNA (0.57) | TSHRMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9071562-A | — | — | None | — | — | JP | disclosed |
| JP-H0971562-A | THIOCARBAMIC ACID DERIVATIVE | GREEN CROSS CORP:THE | 1997-03-18 | — | — | JP | disclosed |