Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819418 | 0.81 | MMP12 (0.38) | CA12CA2CA9L3MBTL1KDM4E | |
| SCHEMBL12932625 | 0.81 | AOC3 (0.44) | CA12CA2CA9 | |
| SCHEMBL10473979 | 0.79 | TSHR (0.44) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL19158147 | 0.79 | MAPT (0.49) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8845291 | 0.76 | MAOB (0.44) | ALDH1A1TSHR | |
| SCHEMBL7243914 | 0.75 | MEN1 (0.44) | CA12CA2CA9ALDH1A1LMNA | |
| SCHEMBL8281045 | 0.74 | TSHR (0.45) | KDM4EALDH1A1HTR2AMAPTGAA | |
| SCHEMBL1554057 | 0.70 | HTR2A (0.48) | CA12CA2CA9L3MBTL1KDM4E | |
| SCHEMBL2600473 | 0.70 | CA12 (0.44) | CA12CA2CA9KDM4EALDH1A1 | |
| SCHEMBL14586288 | 0.69 | TRPA1 (0.44) | TAAR1CYP2D6SLC6A2SLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898941-A | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0257591-A2 | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |