Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL922024 | 0.73 | KDM4E (0.35) | KDM4ECRHBPCRHR2MEN1KMT2A | |
| SCHEMBL8840526 | 0.71 | HTT (0.40) | KDM4ECRHBPCRHR2MEN1KMT2A | |
| Hydrogen Peroxide SCHEMBL11574286 | 0.71 | FABP3 (0.44) | KDM4EALDH1A1HTTACHEFABP3 | |
| SCHEMBL9622672 | 0.70 | KDM4E (0.42) | KDM4EMEN1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL564831 | 0.70 | AKR1C3 (0.58) | MEN1KMT2AALDH1A1HTTAKR1C3 | |
| SCHEMBL8845375 | 0.68 | KDM4E (0.38) | KDM4EKMT2AALDH1A1HTTPOLB | |
| SCHEMBL8845368 | 0.68 | KDM4E (0.38) | KDM4EALDH1A1HTTBCHEACHE | |
| Hydrogen Peroxide SCHEMBL11210753 | 0.67 | FABP3 (0.44) | KDM4EALDH1A1HTTACHEFABP3 | |
| SCHEMBL3363012 | 0.66 | LMNA (0.40) | KDM4EALDH1A1HTTACHEFABP3 | |
| SCHEMBL23354337 | 0.66 | CYP2D6 (0.44) | ALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595992-A | Substituted pyridines and pyrimidines, processes for their preparation and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-21 | — | — | US | disclosed |