Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.33 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.33 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.33 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622672 | 0.76 | KDM4E (0.42) | KDM4ERAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL29757496 | 0.76 | KDM4E (0.36) | KDM4ERAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL922026 | 0.76 | KDM4E (0.36) | KDM4ERAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL8840533 | 0.74 | KDM4E (0.37) | KDM4ESMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL16961382 | 0.71 | HTT (0.46) | KDM4EHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL101014 | 0.70 | KDM4E (0.41) | KDM4EHPGDLMNAPOLBALDH1A1 | |
| SCHEMBL3366219 | 0.69 | KDM4E (0.33) | KDM4EHTTALDH1A1 | |
| SCHEMBL15787178 | 0.68 | MAOA (0.38) | KDM4EHTTALDH1A1 | |
| SCHEMBL6747628 | 0.68 | SMN1; SMN2 (0.43) | KDM4ERAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL8845372 | 0.68 | KDM4E (0.38) | KDM4EHTTPOLBALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5595992-A | Substituted pyridines and pyrimidines, processes for their preparation and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-21 | — | — | US | disclosed |