Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29715211 | 0.87 | KDM4E (0.43) | CA1CA2CA12CA9CA14 | |
| SCHEMBL4873009 | 0.87 | KDM4E (0.43) | CA1CA2CA12CA9CA14 | |
| SCHEMBL242556 | 0.87 | KDM4E (0.43) | CA1CA2CA12CA9CA14 | |
| SCHEMBL242555 | 0.87 | KDM4E (0.43) | CA1CA2CA12CA9CA14 | |
| SCHEMBL16269615 | 0.87 | KDM4E (0.43) | CA1CA2CA12CA9CA14 | |
| Methane SCHEMBL10504286 | 0.86 | KDM4E (0.42) | CA1CA2CA12CA9CA14 | |
| SCHEMBL1226636 | 0.83 | KDM4C (0.50) | KDM4CCA1CA2CA12CA9 | |
| SCHEMBL27486347 | 0.83 | MAPT (0.49) | CA1CA2CA12CA9CA14 | |
| SCHEMBL24276931 | 0.82 | MEN1 (0.51) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL9413247 | 0.80 | TSHR (0.53) | CA1CA2CA12CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625081-A | XANTHENE DYE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5608063-A | Method, system and reagents for DNA sequencing | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5558991-A | DNA sequencing method using acyclonucleoside triphosphates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0309969-B1 | Method of gene mapping | DU PONT (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0252683-B1 | Process and reagents for DNA sequence analysis | DU PONT (US) | 1995-01-18 | — | — | EP | disclosed |
| US-5332666-A | Reporter-labeled chain terminator reacted with DNA nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| US-5306618-A | Using xanthene dye reporter labeled DNA fragments | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5242796-A | Fluorescent xanthene dye | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0185547-B1 | POLYNUCLEOTIDE HYBRIDIZATION ASSAYS EMPLOYING CATALYZED LUMINESCENCE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |
| US-5102785-A | Cleaving to produce DNA fragment which are then end labeled with reporter, again cleaved to produce short fragment, separatiion; analysis | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0309969-A2 | Method of gene mapping | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4670379-A | Polynucleotide hydridization assays employing catalyzed luminescence | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0185547-A2 | Polynucleotide hybridization assays employing catalyzed luminescence | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-06-25 | — | — | EP | disclosed |