SCHEMBL242555

SCHEMBL242555

CC(Nc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.43
GAA P10253 4/20 0.43
RECQL P46063 2/20 0.43
DBH P09172 1/20 0.43
TDP1 Q9NUW8 5/20 0.42
ALOX15 P16050 4/20 0.42
HSD17B10 Q99714 4/20 0.42
HIF1A Q16665 3/20 0.42
PTGS2 P35354 2/20 0.42
USP2 O75604 1/20 0.42
EGFR P00533 1/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
PTGS1 P23219 1/20 0.42
HTR2A P28223 1/20 0.42
SLC7A5 Q01650 1/20 0.42
TOP1 P11387 1/20 0.42
ERCC1 P07992 2/20 0.41
ERCC4 Q92889 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16269615 1.00 KDM4E (0.43) KDM4EGAARECQLDBHTDP1
SCHEMBL242556 1.00 KDM4E (0.43) KDM4EGAARECQLDBHTDP1
SCHEMBL4873009 1.00 KDM4E (0.43) KDM4EGAARECQLDBHTDP1
SCHEMBL29715211 1.00 KDM4E (0.43) KDM4EGAARECQLDBHTDP1
Methane SCHEMBL10504286 0.98 KDM4E (0.42) KDM4EGAARECQLDBHTDP1
SCHEMBL8845474 0.87 KDM5A (0.38) KDM4EGAARECQLDBHTDP1
SCHEMBL28970772 0.84 CA2 (0.39) KDM4EGAARECQLTDP1ALOX15
SCHEMBL2745069 0.84 KMT2A (0.50) KDM4EGAATDP1HSD17B10MAPT
SCHEMBL27486347 0.84 MAPT (0.49) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL1226636 0.84 KDM4C (0.50) KDM4ETDP1HSD17B10PTGS2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106592230-B A kind of preparation method for the antibacterial biological biocompatible fabric that high surface potential mediates 苏州度博迈医疗科技有限公司 2019-09-13 CN claimed
CN-106592230-A Preparation method for high surface potential mediated antibacterial biocompatible fabric 苏州度博迈医疗科技有限公司 2017-04-26 CN claimed
US-9421164-B2 Stimuli responsive adhesive gel for removal of foreign particles from soft tissue CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2016-08-23 US claimed
EP-2334305-B1 BIOADHESIVE CONSTRUCTS KENSEY NASH CORP (US) 2015-04-22 EP claimed
US-20140315955-A1 STIMULI RESPONSIVE ADHESIVE GEL FOR REMOVAL OF FOREIGN PARTICLES FROM SOFT TISSUE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2014-10-23 US claimed
US-8809274-B2 Adhesive hemostatic agent based on porcine atelocollagen and method for production thereof DALIM BIOTECH CO., LTD. (KR) 2014-08-19 US claimed
US-8791219-B2 Rapidly crosslinkable adhesives for biomedical applications CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2014-07-29 US claimed
US-8673286-B2 DOPA-functionalized, branched, poly(aklylene oxide) adhesives NORTHWESTERN UNIVERSITY (US) 2014-03-18 US claimed
US-20130248109-A1 RAPIDLY CROSSLINKABLE ADHESIVES FOR BIOMEDICAL APPLICATIONS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-09-26 US claimed
WO-2013142028-A1 RAPIDLY CROSSLINKABLE ADHESIVES FOR BIOMEDICAL APPLICATIONS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2013-09-26 WO claimed
EP-1641930-A2 NUCLEIC ACID SEQUENCES ENCODING PROTEINS ASSOCIATED WITH ABIOTIC STRESS RESPONSE AND PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF Plant Science GmbH (DE) 2006-04-05 EP claimed
WO-2005047409-A1 POLISHING COMPOSITION AND POLISHING METHOD SHOWA DENKO K.K. (JP) 2005-05-26 WO claimed
US-20040261198-A1 Restructuring and finishing of keratin fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-12-30 US claimed
WO-2004092398-A2 NUCLEIC ACID SEQUENCES ENCODING PROTEINS ASSOCIATED WITH ABIOTIC STRESS RESPONSE AND PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF PLANT SCIENCE GMBH (DE) 2004-10-28 WO claimed
US-20030045725-A1 Method for the production of aromatic or heteroaromatic aldehydes or ketones by oxidative decarboxylation DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2003-03-06 US claimed
EP-0750490-B1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KGAA (DE) 2000-11-08 EP claimed
US-5743919-A HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-04-28 US claimed
US-5611817-A HAIR DYES, COLORFASTNESS HENKEL AG & CO. KGAA (DE) 1997-03-18 US claimed
EP-0695163-B1 ISATIN DERIVATIVES FOR DYEING KERATIN-CONTAINING FIBRES HENKEL KGAA (DE) 1997-03-05 EP claimed
US-4380646-A Method for the N-acylation of aminocarboxylic acids DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1983-04-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030045725-A1 Method for the production of aromatic or heteroaromatic aldehydes or ketones by oxidative decarboxylation AOX1, ALDH5A1, AOC2 KDM4E 1466/4885GAA 852/4885RECQL 3961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.