SCHEMBL4873009

SCHEMBL4873009

C[C@@H](Nc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.43
GAA P10253 4/20 0.43
RECQL P46063 2/20 0.43
DBH P09172 1/20 0.43
TDP1 Q9NUW8 5/20 0.42
ALOX15 P16050 4/20 0.42
HSD17B10 Q99714 4/20 0.42
HIF1A Q16665 3/20 0.42
PTGS2 P35354 2/20 0.42
USP2 O75604 1/20 0.42
EGFR P00533 1/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
PTGS1 P23219 1/20 0.42
HTR2A P28223 1/20 0.42
SLC7A5 Q01650 1/20 0.42
TOP1 P11387 1/20 0.42
ERCC1 P07992 2/20 0.41
ERCC4 Q92889 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16269615 1.00 KDM4E (0.43) KDM4EGAARECQLDBHTDP1
SCHEMBL242556 1.00 KDM4E (0.43) KDM4EGAARECQLDBHTDP1
SCHEMBL29715211 1.00 KDM4E (0.43) KDM4EGAARECQLDBHTDP1
SCHEMBL242555 1.00 KDM4E (0.43) KDM4EGAARECQLDBHTDP1
Methane SCHEMBL10504286 0.98 KDM4E (0.42) KDM4EGAARECQLDBHTDP1
SCHEMBL8845474 0.87 KDM5A (0.38) KDM4EGAARECQLDBHTDP1
SCHEMBL28970772 0.84 CA2 (0.39) KDM4EGAARECQLTDP1ALOX15
SCHEMBL2745069 0.84 KMT2A (0.50) KDM4EGAATDP1HSD17B10MAPT
SCHEMBL27486347 0.84 MAPT (0.49) KDM4EGAAMAPTMEN1KMT2A
SCHEMBL1226636 0.84 KDM4C (0.50) KDM4ETDP1HSD17B10PTGS2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7365142-B2 Polyelectrolyte complex films for analytical and membrane separation of chiral compounds FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2008-04-29 US disclosed
US-20070037948-A1 Porous substrates; chromatography packing; caplllary tubes; contacting a solution comprising the enantiomers with a membrane that interacts with the enantiomers in an enantioselective manner and separating the enantiomers by passage through the membrane FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2007-02-15 US disclosed
US-7101947-B2 Polyelectrolyte complex films for analytical and membrane separation of chiral compounds FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2006-09-05 US disclosed
US-20040044100-A1 Polyelectrolyte complex films for analytical and membrane separation of chiral compounds FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2004-03-04 US disclosed