SCHEMBL8845484

SCHEMBL8845484

CNC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)CC1O

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TK1 P04183 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8845478 1.00 TK1 (0.65) TK1
SCHEMBL6323289 0.89
SCHEMBL6323285 0.89
Hydrochloric Acid SCHEMBL6322576 0.88
Hydrochloric Acid SCHEMBL6322571 0.88
SCHEMBL9484016 0.88
SCHEMBL11600923 0.88
SCHEMBL11600919 0.88
SCHEMBL655193 0.88 TK1 (0.67) TK1
SCHEMBL9780740 0.87 TK2 (0.65) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5625081-A XANTHENE DYE DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-04-29 US disclosed
US-5608063-A Method, system and reagents for DNA sequencing E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-03-04 US disclosed
US-5558991-A DNA sequencing method using acyclonucleoside triphosphates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-24 US disclosed
EP-0252683-B1 Process and reagents for DNA sequence analysis DU PONT (US) 1995-01-18 EP disclosed
US-5332666-A Reporter-labeled chain terminator reacted with DNA nucleotides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-07-26 US disclosed
US-5306618-A Using xanthene dye reporter labeled DNA fragments E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-04-26 US disclosed
US-5242796-A Fluorescent xanthene dye E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-07 US disclosed