SCHEMBL884549

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL884402	0.96	PTGIR (0.36)	RENALDH1A1TSHRCYP3A4CYP2D6
	SCHEMBL2062724	0.93	PTGIR (0.34)	RENALDH1A1TSHRCYP3A4CYP2D6
	SCHEMBL885504	0.92	ALDH1A1 (0.42)	ALDH1A1TSHRCYP3A4CYP2D6USP2
	SCHEMBL2062941	0.91	KDM4E (0.38)	ALDH1A1TSHRCYP3A4CYP2D6USP2
	SCHEMBL884600	0.91	KDM4E (0.40)	ALDH1A1TSHRMEN1KMT2AKDM4E
	SCHEMBL884381	0.90	KMT2A (0.39)	ALDH1A1TSHRCYP2D6USP2CYP2C19
	SCHEMBL884366	0.89	PTGIR (0.37)	ALDH1A1TSHRCYP3A4CYP2D6USP2
	SCHEMBL884782	0.89	REN (0.38)	RENALDH1A1CYP2C19MEN1KMT2A
	SCHEMBL884884	0.88	PTGIR (0.36)	ALDH1A1TSHRCASP1CASP7KMT2A
	SCHEMBL2062942	0.87	CYP2D6 (0.37)	RENALDH1A1TSHRCYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.