Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | LSS | P48449 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10574784 | 0.99 | LTA4H (0.56) | LTA4HLSSHRH3HTR6LMNA | |
| SCHEMBL11061377 | 0.94 | HRH3 (0.53) | LTA4HHRH3MAPTKDM4EESR1 | |
| Hydrochloric Acid SCHEMBL11061505 | 0.92 | HRH3 (0.51) | LTA4HHRH3MAPTKDM4EESR1 | |
| SCHEMBL11057521 | 0.91 | LTA4H (0.49) | LTA4HHRH3HTR6LMNAMAPT | |
| Sulfuric Acid SCHEMBL11060751 | 0.86 | HRH3 (0.48) | LTA4HHRH3MAPTKDM4EESR1 | |
| SCHEMBL8845624 | 0.86 | HTT (0.57) | LTA4HHRH3HTR6MAPTKDM4E | |
| SCHEMBL8845562 | 0.82 | MEN1 (0.43) | LTA4HHRH3LMNAMAPTKDM4E | |
| SCHEMBL22595039 | 0.81 | LTA4H (0.52) | LTA4HLSSHRH3HTR6LMNA | |
| SCHEMBL8845580 | 0.80 | ALDH1A1 (0.56) | MAPTMEN1NR1I2CYP3A4DRD2 | |
| SCHEMBL8915518 | 0.80 | LTA4H (0.55) | LTA4HLSSHRH3HTR6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658914-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |
| US-5658951-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |
| US-5658927-A | ANTIESTROGENS, ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-08-19 | — | — | US | disclosed |
| US-5422367-A | A hormon inhibitors and for inhibiting the development of an estrogen-dependent tumor | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-06-06 | — | — | US | disclosed |
| US-5324736-A | Diphenylcyclopropyl analogs as antiestrogenic and antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-06-28 | — | — | US | disclosed |
| US-5098903-A | Halocyclopropanes | BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 1992-03-24 | — | — | US | disclosed |