Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 12/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 4/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845526 | 0.78 | HMGB1 (0.31) | — | |
| SCHEMBL8845451 | 0.69 | MAOB (0.41) | TYR | |
| SCHEMBL13335379 | 0.68 | ESR1 (0.46) | TYRESR1ESR2SLC22A8SLC22A6 | |
| Urea SCHEMBL27878783 | 0.59 | ESR2 (0.37) | TYRESR1ESR2 | |
| Acetic Acid SCHEMBL7711008 | 0.59 | CSNK2A1 (0.44) | ESR1ESR2 | |
| SCHEMBL13542765 | 0.58 | TYR (0.40) | TYR | |
| SCHEMBL9594206 | 0.58 | TYR (0.46) | TYRESR1ESR2 | |
| SCHEMBL33480 | 0.58 | — | — | |
| SCHEMBL12316602 | 0.58 | ESR1 (0.51) | TYRESR1ESR2 | |
| SCHEMBL30251104 | 0.58 | ESR1 (0.51) | TYRESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625081-A | XANTHENE DYE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5608063-A | Method, system and reagents for DNA sequencing | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5558991-A | DNA sequencing method using acyclonucleoside triphosphates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0309969-B1 | Method of gene mapping | DU PONT (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0252683-B1 | Process and reagents for DNA sequence analysis | DU PONT (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0251786-B1 | Alkynylamino-nucleotides | DU PONT (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5332666-A | Reporter-labeled chain terminator reacted with DNA nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| US-5306618-A | Using xanthene dye reporter labeled DNA fragments | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5242796-A | Fluorescent xanthene dye | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| US-5151507-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5102785-A | Cleaving to produce DNA fragment which are then end labeled with reporter, again cleaved to produce short fragment, separatiion; analysis | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-5047519-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0309969-A2 | Method of gene mapping | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| EP-0252683-A2 | Process and reagents for DNA sequence analysis | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
| EP-0251786-A2 | Alkynylamino-nucleotides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |