Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | TYR | P14679 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | YWHAG | P61981 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13542765 | 0.86 | TYR (0.40) | MAOBTYRMAOAMEN1KMT2A | |
| SCHEMBL12693590 | 0.75 | MAOA (0.37) | MAOBTYRMAOAMEN1KMT2A | |
| SCHEMBL8845603 | 0.69 | TYR (0.39) | TYR | |
| SCHEMBL8845448 | 0.68 | MEN1 (0.43) | MAOBTYRMAOAMEN1KMT2A | |
| SCHEMBL23460330 | 0.65 | MAOA (0.43) | MAOBTYRMAOAMEN1KMT2A | |
| SCHEMBL29919352 | 0.65 | MAOA (0.43) | MAOBTYRMAOAMEN1KMT2A | |
| SCHEMBL8845526 | 0.65 | HMGB1 (0.31) | — | |
| SCHEMBL22046626 | 0.65 | MAOB (0.48) | MAOBTYRMAOAMEN1KMT2A | |
| Isoaurostatin SCHEMBL15426107 | 0.65 | MAOA (0.63) | MAOBTYRMAOAMEN1KMT2A | |
| Isoaurostatin SCHEMBL29551912 | 0.65 | MAOA (0.63) | MAOBTYRMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625081-A | XANTHENE DYE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5608063-A | Method, system and reagents for DNA sequencing | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5558991-A | DNA sequencing method using acyclonucleoside triphosphates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0309969-B1 | Method of gene mapping | DU PONT (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0252683-B1 | Process and reagents for DNA sequence analysis | DU PONT (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0251786-B1 | Alkynylamino-nucleotides | DU PONT (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5332666-A | Reporter-labeled chain terminator reacted with DNA nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| US-5306618-A | Using xanthene dye reporter labeled DNA fragments | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5242796-A | Fluorescent xanthene dye | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| US-5151507-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5102785-A | Cleaving to produce DNA fragment which are then end labeled with reporter, again cleaved to produce short fragment, separatiion; analysis | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-5047519-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0309969-A2 | Method of gene mapping | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| EP-0252683-A2 | Process and reagents for DNA sequence analysis | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
| EP-0251786-A2 | Alkynylamino-nucleotides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |