Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845451 | 0.86 | MAOB (0.41) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL12693590 | 0.77 | MAOA (0.37) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL8845448 | 0.70 | MEN1 (0.43) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL20099452 | 0.70 | CRHBP (0.44) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL23460330 | 0.64 | MAOA (0.43) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL29919352 | 0.64 | MAOA (0.43) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL22046626 | 0.64 | MAOB (0.48) | TYRMAOAMAOBMEN1KMT2A | |
| Isoaurostatin SCHEMBL15426107 | 0.64 | MAOA (0.63) | TYRMAOAMAOBMEN1KMT2A | |
| Isoaurostatin SCHEMBL29551912 | 0.64 | MAOA (0.63) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL22731985 | 0.64 | TYR (0.31) | TYRMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440635-B2 | Oligonucleotide conjugates | GERON CORPORATION (US) | 2013-05-14 | — | — | US | disclosed |
| US-20100016416-A1 | Oligonucleotide Conjugates | GERON CORPORATION (US) | 2010-01-21 | — | — | US | disclosed |
| US-7563618-B2 | Oligonucleotide conjugates | GERON CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016416-A1 | Oligonucleotide Conjugates | TERT, RNGTT, TRDMT1 | TYR 127/4885MAOA 652/4885MAOB 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.