Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206957 | 0.85 | TP53 (0.44) | TP53OPRM1SPHK1ACE2CA2 | |
| SCHEMBL22504911 | 0.76 | DNM1 (0.57) | OPRM1DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL9899017 | 0.74 | TP53 (0.42) | TP53OPRM1TSHRSPHK1CA2 | |
| SCHEMBL28324324 | 0.73 | TP53 (0.53) | TP53OPRM1SPHK1GNAI3GNAO1 | |
| SCHEMBL19708567 | 0.70 | ACE2 (0.55) | OPRM1DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL13520175 | 0.69 | DNM1 (0.52) | TP53OPRM1DNM1MEN1KMT2A | |
| SCHEMBL11495281 | 0.69 | DNM1 (0.52) | OPRM1DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL11035498 | 0.69 | DPP8 (0.41) | OPRM1DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL24835048 | 0.68 | DNM1 (0.57) | OPRM1DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL3625787 | 0.68 | DNM1 (0.57) | OPRM1DNM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693643-A | FOR PREVENTING PREMATAURE LABOR, STOPPING LABOR BEFORE A CESARIAN DELIVERY AND TREATING DYSMENORRHEA | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |