Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154539 | 0.76 | ITGB3 (0.37) | ALDH1A1NAMPTHRH3EPHX2 | |
| SCHEMBL8846256 | 0.74 | TP53 (0.43) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL8845762 | 0.70 | BCHE (0.47) | ALDH1A1EPHX2ACHE | |
| SCHEMBL30376267 | 0.67 | HDAC1 (0.47) | HDAC1HDAC6ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9154489 | 0.66 | EPHX2 (0.44) | HDAC6EPHX2ACHE | |
| SCHEMBL9652573 | 0.65 | HRH3 (0.38) | ALDH1A1MEN1KMT2AL3MBTL1HRH3 | |
| SCHEMBL16494203 | 0.64 | GRIN2B (0.52) | ALDH1A1MEN1KMT2AGRM5 | |
| SCHEMBL8777936 | 0.64 | TP53 (0.52) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL8845748 | 0.62 | DRD4 (0.36) | MEN1KMT2ATP53MGAT2 | |
| SCHEMBL8778013 | 0.62 | MEN1 (0.47) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556308-B1 | OXYSULFONYL UREA ACAT INHIBITORS | WARNER LAMBERT CO (US) | 1995-02-01 | — | — | EP | claimed |
| US-5688816-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-18 | — | — | US | disclosed |