SCHEMBL8845792

SCHEMBL8845792

CCCc1nc(CO)c(C(=O)OCC)n1Cc1cccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 9/20 0.52
AGTR2 P50052 9/20 0.52
AGT P01019 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7303260 0.92 AGTR1 (0.61) AGTR1AGTR2AGT
SCHEMBL14855371 0.88 AGT (0.60) AGTR1AGTR2AGT
SCHEMBL14855449 0.87 AGTR1 (0.62) AGTR1AGTR2AGT
SCHEMBL14855464 0.87 AGTR1 (0.62) AGTR1AGTR2AGT
SCHEMBL14855413 0.86 AGTR1 (0.59) AGTR1AGTR2AGT
SCHEMBL7908421 0.85 AGTR1 (0.57) AGTR1AGTR2AGT
SCHEMBL7310107 0.84 AGTR1 (0.63) AGTR1AGTR2AGT
SCHEMBL7301221 0.84 AGTR1 (0.64) AGTR1AGTR2
SCHEMBL14855157 0.84 AGTR1 (0.52) AGTR1AGTR2AGT
SCHEMBL7312731 0.84 AGTR1 (0.60) AGTR1AGTR2AGT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5646171-A HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 1997-07-08 US disclosed