SCHEMBL8845815

SCHEMBL8845815

CC1(C)C=CC(/C=C/C(=O)c2ccccc2)C=C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.45
MAPT P10636 6/20 0.44
ALDH1A1 P00352 6/20 0.44
NPSR1 Q6W5P4 5/20 0.44
LMNA P02545 3/20 0.44
PLIN1 O60240 2/20 0.44
PLIN5 Q00G26 2/20 0.44
ABHD5 Q8WTS1 2/20 0.44
HPGD P15428 2/20 0.44
HTT P42858 1/20 0.44
BCHE P06276 2/20 0.43
CYP1B1 Q16678 2/20 0.43
TNFRSF1A P19438 1/20 0.43
ACHE P22303 1/20 0.43
MAOB P27338 1/20 0.43
MAPK1 P28482 3/20 0.42
MDM2 Q00987 1/20 0.42
KMT2A Q03164 5/20 0.42
MEN1 O00255 3/20 0.42
NFKB1 P19838 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10425119 0.85 MAPT (0.45) RECQLMAPTALDH1A1NPSR1LMNA
SCHEMBL6500192 0.85 RECQL (0.41) RECQLMAPTALDH1A1NPSR1LMNA
SCHEMBL1470131 0.84 RECQL (0.50) RECQLMAPTALDH1A1NPSR1LMNA
SCHEMBL9439994 0.84 MAPT (0.44) RECQLMAPTALDH1A1NPSR1LMNA
SCHEMBL5928954 0.84 AKT1 (0.43) RECQLMAPTALDH1A1NPSR1LMNA
SCHEMBL9040004 0.84 AKT1 (0.43) RECQLMAPTALDH1A1NPSR1LMNA
SCHEMBL11826827 0.82 MAPT (0.42) RECQLMAPTALDH1A1NPSR1LMNA
SCHEMBL814596 0.80 RECQL (0.42) RECQLMAPTALDH1A1NPSR1LMNA
Hydrochloric Acid SCHEMBL11816675 0.79 ALDH1A1 (0.40) RECQLMAPTALDH1A1NPSR1LMNA
SCHEMBL12484187 0.74 RECQL (0.40) RECQLMAPTALDH1A1NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096455-B Preparation method of modified alkyl phenolic tackifying resin and rubber composition thereof 山东圣泉新材料股份有限公司 2021-07-06 CN disclosed
EP-0693502-B1 Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same MITSUBISHI CHEM CORP (JP) 1997-11-05 EP disclosed
US-5594081-A METALLOCENES MITSUBISHI CHEMICAL CORPORATION (JP) 1997-01-14 US disclosed
EP-0693502-A1 Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same MITSUBISHI CHEMICAL CORPORATION (JP) 1996-01-24 EP disclosed