SCHEMBL8845873

SCHEMBL8845873

C#CCC(O)CC(OCC)OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187477 0.77 THRB (0.38)
SCHEMBL11277204 0.70
SCHEMBL21239268 0.70 THRB (0.40)
SCHEMBL10314780 0.69
SCHEMBL10314775 0.69
SCHEMBL487643 0.69
SCHEMBL46524 0.68 THRB (0.50)
SCHEMBL3196665 0.68
SCHEMBL28822895 0.67 THRB (0.38)
SCHEMBL25174850 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738251-A4 PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESES OF VITAMIN D AND ANALOGUES UNIV LELAND STANFORD JUNIOR (US) 1997-05-14 EP disclosed
EP-0738251-A1 PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESES OF VITAMIN D AND ANALOGUES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1996-10-23 EP disclosed
US-5446225-A Reacting halide or pseudohalide with 1,6 or 1,7 enyne in presence of palladium catalyst BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV. (US) 1995-08-29 US disclosed
EP-0630361-A4 PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESIS OF VITAMIN D AND ANALOGUES. UNIV LELAND STANFORD JUNIOR (US) 1995-08-23 EP disclosed
WO-1995017363-A1 PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESES OF VITAMIN D AND ANALOGUES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-06-29 WO disclosed
EP-0630361-A1 PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESIS OF VITAMIN D AND ANALOGUES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1994-12-28 EP disclosed
US-5292977-A Palladium catalyzed alkylative cyclization useful in synthesis of vitamin D and analogues BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) 1994-03-08 US disclosed
WO-1993016022-A1 PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESIS OF VITAMIN D AND ANALOGUES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1993-08-19 WO disclosed