Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090328 | 0.75 | LMNA (0.47) | HCAR2LMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL3090330 | 0.75 | LMNA (0.47) | HCAR2LMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL15095465 | 0.71 | ALDH1A1 (0.58) | HCAR2LMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27821458 | 0.67 | ALDH1A1 (0.45) | ALDH1A1DDB1CRBN | |
| SCHEMBL11321667 | 0.67 | DDB1 (0.50) | HCAR2LMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL16370383 | 0.66 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL2905233 | 0.66 | HCAR2 (0.36) | HCAR2PKMCA12AKR1B10AKR1B1 | |
| SCHEMBL12027689 | 0.66 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1DDB1CRBN | |
| SCHEMBL31158250 | 0.66 | HCAR2 (0.31) | HCAR2 | |
| SCHEMBL17685852 | 0.65 | ALDH1A1 (0.36) | HCAR2ALDH1A1MAPK1L3MBTL1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |