Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 3/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.44 |
| ▸ | RARG | P13631 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | GOT1 | P17174 | 1/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318535 | 0.88 | S1PR1 (0.53) | CNR1CNR2STSRARARARB | |
| SCHEMBL8845914 | 0.85 | S1PR1 (0.40) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8846460 | 0.85 | S1PR1 (0.43) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL566311 | 0.85 | CNR1 (0.42) | CNR1CNR2STSRARARARB | |
| SCHEMBL18932787 | 0.82 | RARA (0.41) | CNR1CNR2STSRARARARB | |
| SCHEMBL18932810 | 0.82 | CNR1 (0.37) | CNR1CNR2STSRARARARB | |
| SCHEMBL979019 | 0.79 | RARB (0.67) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL29462719 | 0.79 | RARB (0.67) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL18043697 | 0.78 | CNR2 (0.48) | CNR2RARARARBRARGMEN1 | |
| SCHEMBL3309247 | 0.77 | HDAC11 (0.43) | CNR2RARARARBRARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664282-B1 | Biaryl phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0664282-A1 | Biaryl phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-26 | — | — | EP | disclosed |
| US-5391817-A | Antiinflammatory agents | BRISTOL-MYERS SQUIBB (US) | 1995-02-21 | — | — | US | disclosed |