Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.67 |
| ▸ | RARG | P13631 | 10/20 | 0.67 |
| ▸ | RARA | P10276 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.67 |
| ▸ | GOT1 | P17174 | 1/20 | 0.67 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462719 | 1.00 | RARB (0.67) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL5828464 | 0.88 | RARB (0.64) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL21746062 | 0.88 | RARB (0.64) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL3318535 | 0.87 | S1PR1 (0.53) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL25253159 | 0.85 | RARB (0.64) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL30510654 | 0.85 | RARB (0.64) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL1196174 | 0.84 | RARB (0.71) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL26688920 | 0.84 | RARB (0.64) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL5827886 | 0.84 | RARB (0.70) | RARBRARGRARAMEN1KMT2A | |
| Adapalene SCHEMBL21724948 | 0.83 | RARB (0.83) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150098918-A1 | CREAM GELS COMPRISING AT LEAST ONE RETINOID AND BENZOYL PEROXIDE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-04-09 | — | — | US | claimed |
| US-20100166852-A1 | Cream gels comprising at least one retinoid and benzoyl peroxide | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-07-01 | — | — | US | claimed |
| US-20090318550-A1 | Emulsions comprising at least one retinoid and benzoyl peroxide | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-12-24 | — | — | US | claimed |
| US-RE34805-E | Treatment of dermatologic diseases, degeneration of conjunctive tissues; antitumor activity | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1994-12-06 | — | — | US | claimed |
| US-4940696-A | Benzonaphthalene derivatives and their use in therapeutic and cosmetic compositions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIOUES (CIRD) (FR) | 1990-07-10 | — | — | US | claimed |
| EP-0199636-B1 | BENZONAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PHARMACY AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. Groupement d'Intérêt Economique dit: (FR) | 1989-02-08 | — | — | EP | claimed |
| EP-0199636-A1 | Benzonaphthalenic derivatives, process for their preparation and their use in pharmacy and cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. Groupement d'Intérêt Economique dit: (FR) | 1986-10-29 | — | — | EP | claimed |
| US-12195424-B2 | Antibiotic compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2025-01-14 | — | — | US | disclosed |
| US-20230346727-A1 | COMPOUNDS FOR THE TREATMENT OF HEMOPHILIA | UNIVERSITE GRENOBLE ALPES (FR) | 2023-11-02 | — | — | US | disclosed |
| US-20230346727-A1 | COMPOUNDS FOR THE TREATMENT OF HEMOPHILIA | UNIVERSITE GRENOBLE ALPES (FR) | 2023-11-02 | — | — | US | disclosed |
| US-20230346727-A1 | COMPOUNDS FOR THE TREATMENT OF HEMOPHILIA | UNIVERSITE GRENOBLE ALPES (FR) | 2023-11-02 | — | — | US | disclosed |
| CN-116710080-A | Compounds for treatment of hemophilia | 格勒诺布尔大学 | 2023-09-05 | — | — | CN | disclosed |
| EP-4185281-A1 | COMPOUNDS FOR THE TREATMENT OF HAEMOPHILIA | Université Grenoble Alpes (FR) | 2023-05-31 | — | — | EP | disclosed |
| US-5212303-A | Benzonaphthalene derivatives, a process for their preparation and their use in therapeutic and cosmetic compositions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1993-05-18 | — | — | US | disclosed |
| US-5183889-A | For topical or systemic treatment of dermatologic disease, degeneration of conjunction tissues and tumors | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1993-02-02 | — | — | US | disclosed |
| US-5098895-A | Skin disorders and antitumor agents | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1992-03-24 | — | — | US | disclosed |
| US-4940696-A | Benzonaphthalene derivatives and their use in therapeutic and cosmetic compositions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIOUES (CIRD) (FR) | 1990-07-10 | — | — | US | disclosed |
| EP-0199636-B1 | BENZONAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PHARMACY AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. Groupement d'Intérêt Economique dit: (FR) | 1989-02-08 | — | — | EP | disclosed |
| US-4717720-A | DERMATOLOGIC DISEASES, CONJUCTIVE TISSUE DEGENERATION AND ANTI-TUMOR ACTIVITY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1988-01-05 | — | — | US | disclosed |
| EP-0199636-A1 | Benzonaphthalenic derivatives, process for their preparation and their use in pharmacy and cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. Groupement d'Intérêt Economique dit: (FR) | 1986-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346727-A1 | COMPOUNDS FOR THE TREATMENT OF HEMOPHILIA | PROC, F2, F8 | RARB 1848/4885RARG 1713/4885RARA 1675/4885 |
| US-12195424-B2 | Antibiotic compounds | CUTA, NRDC, CLPP | RARB 26/4885RARG 78/4885RARA 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.