SCHEMBL8846200

SCHEMBL8846200

O=C(O)/C=C/C=C/C1(F)CC1c1ccc(Br)c(Br)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
KDM1A O60341 1/20 0.30
RCOR1 Q9UKL0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27356803 0.89 KDM1A (0.32) KDM1ARCOR1
SCHEMBL9196128 0.81 EGFR (0.42)
SCHEMBL9516768 0.81
SCHEMBL9193683 0.79 MMP1 (0.40)
SCHEMBL9190860 0.79 MMP1 (0.39) KDM1A
SCHEMBL9196118 0.79 ALDH1A1 (0.45)
SCHEMBL9191694 0.79 MMP1 (0.40)
SCHEMBL9566249 0.79 HTT (0.33)
SCHEMBL9190956 0.79 MMP1 (0.40)
SCHEMBL9188945 0.79 MMP1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5605912-A INSECTICIDES, MITICIDES ROUSSEL UCLAF (FR) 1997-02-25 US disclosed
EP-0524041-B1 Pesticides ROUSSEL UCLAF (FR) 1995-09-20 EP disclosed
EP-0547972-B1 Heterocyclic amide derivatives and their use as pesticides ROUSSEL UCLAF (FR) 1995-03-22 EP disclosed
US-5380733-A Certain pyridyl-5-phenyl-1-cyclopropyl-dienamide pesticides ROUSSEL UCLAF (FR) 1995-01-10 US disclosed
EP-0547972-A1 Heterocyclic amide derivatives and their use as pesticides ROUSSEL-UCLAF (FR) 1993-06-23 EP disclosed
EP-0524041-A2 Pesticides ROUSSEL UCLAF (FR) 1993-01-20 EP disclosed