Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 2/20 | 0.34 |
| ▸ | ADH1A | P07327 | 2/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533018 | 0.80 | ADH1A (0.42) | ADH1CADH1A | |
| SCHEMBL270774 | 0.80 | TSHR (0.35) | TSHRSMN1; SMN2ADH1CADH1AADH4 | |
| SCHEMBL270452 | 0.79 | ADH1C (0.35) | TSHRSMN1; SMN2ADH1CADH1AADH4 | |
| SCHEMBL27428739 | 0.77 | ADH1C (0.43) | TSHRADH1CADH1AADH4ADH1B | |
| SCHEMBL18993784 | 0.76 | — | — | |
| SCHEMBL271482 | 0.75 | — | — | |
| SCHEMBL23197945 | 0.74 | TSHR (0.36) | TSHRSMN1; SMN2ADH1CADH1AADH1B | |
| SCHEMBL23959716 | 0.74 | CA12 (0.34) | TSHRSMN1; SMN2ADH1CADH1AADH4 | |
| SCHEMBL29244050 | 0.72 | TDP1 (0.33) | TSHR | |
| SCHEMBL24160923 | 0.72 | CA1 (0.40) | TSHRSMN1; SMN2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767671-A1 | METHOD OF COMBATING ACYCLOVIR-RESISTANT HERPES SIMPLEX VIRAL INFECTIONS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 1997-04-16 | — | — | EP | claimed |
| WO-1994025046-A1 | METHOD OF COMBATING ACYCLOVIR-RESISTANT HERPES SIMPLEX VIRAL INFECTIONS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-11-10 | — | — | WO | claimed |
| WO-1993018056-A1 | ISOSTERIC ANTIHERPES PEPTIDE DERIVATIVES | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1993-09-16 | — | — | WO | disclosed |