Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15346128 | 0.87 | EPHX1 (0.50) | KEAP1NFE2L2EPHX1NPC1SMN1; SMN2 | |
| SCHEMBL29037985 | 0.86 | KEAP1 (0.40) | KEAP1NFE2L2CES2CES1ALDH1A1 | |
| SCHEMBL30031136 | 0.86 | KEAP1 (0.40) | KEAP1NFE2L2CES2CES1NPC1 | |
| SCHEMBL66869 | 0.79 | KEAP1 (0.45) | KEAP1NFE2L2CES2CES1EPHX1 | |
| SCHEMBL28038044 | 0.78 | PDK1 (0.38) | KEAP1NFE2L2EPHX1NPC1RAB9A | |
| SCHEMBL9432704 | 0.77 | KEAP1 (0.34) | KEAP1NFE2L2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2846765 | 0.76 | KEAP1 (0.42) | KEAP1NFE2L2CES2CES1EPHX1 | |
| SCHEMBL8328164 | 0.76 | KEAP1 (0.42) | KEAP1NFE2L2CES2CES1EPHX1 | |
| SCHEMBL873007 | 0.76 | KEAP1 (0.42) | KEAP1NFE2L2CES2CES1EPHX1 | |
| SCHEMBL13518672 | 0.75 | EPHX1 (0.42) | CES2EPHX1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778069-B2 | Phase change inks containing oligomeric rosin esters | XEROX CORPORATION (US) | 2014-07-15 | — | — | US | claimed |
| US-20140137767-A1 | Phase Change Inks Containing Oligomeric Rosin Esters | XEROX CORPORATION (US) | 2014-05-22 | — | — | US | claimed |
| US-5432273-A | Cyclizing a 5-(protected)oxy-5-(heterocyclic base)-3(S)-fluoro-1,2-(S)-pentanediol | EMORY UNIVERSITY (US) | 1995-07-11 | — | — | US | claimed |
| US-5414078-A | Preparation of 3'-substituted-2',3'-dideoxynucleosides and 2'-deoxynucleosides from acyclic, achiral precursors | EMORY UNIVERSITY (US) | 1995-05-09 | — | — | US | claimed |
| WO-1992017485-A1 | PREPARATION OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES AND 2'-DEOXYNUCLEOSIDES FROM ACYCLIC, ACHIRAL PRECURSORS | EMORY UNIVERSITY (US) | 1992-10-15 | — | — | WO | claimed |
| EP-2933246-B1 | VERSATILE AND FUNCTIONALISED INTERMEDIATES FOR THE SYNTHESIS OF VITAMIN D AND NOVEL VITAMIN D DERIVATIVES | ENDOTHERM GMBH (DE) | 2020-01-08 | — | — | EP | disclosed |
| US-20190103634-A1 | Electrolyte for Lithium Secondary Battery and Lithium Secondary Battery Containing the Same | SK INNOVATION CO., LTD. (KR) | 2019-04-04 | — | — | US | disclosed |
| US-9994508-B2 | Versatile and functionalised intermediates for the synthesis of vitamin D and novel vitamin D derivatives | ENDOTHERM GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| CN-105428713-A | Electrolyte for Lithium Secondary Battery and Lithium Secondary Battery Containing the Same | SK INNOVATION CO LTD | 2016-03-23 | — | — | CN | disclosed |
| US-20160079627-A1 | Electrolyte for Lithium Secondary Battery and Lithium Secondary Battery Containing the Same | SK INNOVATION CO., LTD. (KR) | 2016-03-17 | — | — | US | disclosed |
| CN-105406126-A | Electrolyte For Lithium Secondary Battery And Lithium Secondary Battery Containing The Same | SK INNOVATION CO LTD | 2016-03-16 | — | — | CN | disclosed |
| US-20160072150-A1 | Electrolyte for Lithium Secondary Battery and Lithium Secondary Battery Containing the Same | SK INNOVATION CO., LTD. (KR) | 2016-03-10 | — | — | US | disclosed |
| EP-0630361-A4 | PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESIS OF VITAMIN D AND ANALOGUES. | UNIV LELAND STANFORD JUNIOR (US) | 1995-08-23 | — | — | EP | disclosed |
| US-5432273-A | Cyclizing a 5-(protected)oxy-5-(heterocyclic base)-3(S)-fluoro-1,2-(S)-pentanediol | EMORY UNIVERSITY (US) | 1995-07-11 | — | — | US | disclosed |
| WO-1995017363-A1 | PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESES OF VITAMIN D AND ANALOGUES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1995-06-29 | — | — | WO | disclosed |
| US-5414078-A | Preparation of 3'-substituted-2',3'-dideoxynucleosides and 2'-deoxynucleosides from acyclic, achiral precursors | EMORY UNIVERSITY (US) | 1995-05-09 | — | — | US | disclosed |
| EP-0630361-A1 | PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESIS OF VITAMIN D AND ANALOGUES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5292977-A | Palladium catalyzed alkylative cyclization useful in synthesis of vitamin D and analogues | BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY (US) | 1994-03-08 | — | — | US | disclosed |
| WO-1993016022-A1 | PALLADIUM CATALYZED ALKYLATIVE CYCLIZATION USEFUL IN SYNTHESIS OF VITAMIN D AND ANALOGUES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1993-08-19 | — | — | WO | disclosed |
| WO-1992017485-A1 | PREPARATION OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES AND 2'-DEOXYNUCLEOSIDES FROM ACYCLIC, ACHIRAL PRECURSORS | EMORY UNIVERSITY (US) | 1992-10-15 | — | — | WO | disclosed |