Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407846 | 0.82 | TSHR (0.37) | TSHR | |
| SCHEMBL28355468 | 0.81 | MAPT (0.41) | MAPTFAAHTSHR | |
| SCHEMBL8846589 | 0.81 | FAAH (0.37) | MAPTFAAHTSHR | |
| SCHEMBL8846299 | 0.81 | MAPT (0.36) | MAPTFAAHTSHR | |
| SCHEMBL15153946 | 0.79 | TET2 (0.47) | MAPTFAAH | |
| SCHEMBL8846572 | 0.77 | TSHR (0.35) | MAPTFAAHTSHR | |
| SCHEMBL15154020 | 0.77 | FFAR4 (0.40) | MAPTTSHR | |
| SCHEMBL355953 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL8846301 | 0.75 | ALDH1A1 (0.40) | — | |
| SCHEMBL702238 | 0.74 | MAPT (0.42) | MAPTFAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467132-B1 | 4-Substituted-2-hydroxybutanoates and a process for producing them | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5324852-A | Ring opening optically active a-hydroxybutyrolactone; esterification | CHISSO CORPORATION (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0467132-A2 | 4-Substituted-2-hydroxybutanoates and a process for producing them | CHISSO CORPORATION (JP) | 1992-01-22 | — | — | EP | disclosed |