SCHEMBL8846541

SCHEMBL8846541

CCCC(C)C(C)(C)OO

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.33
FDPS P14324 1/20 0.33
METAP1 P53582 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10632090 0.81 TSHR (0.32) TSHR
SCHEMBL325595 0.81 TSHR (0.32) TSHR
SCHEMBL29114518 0.78 TSHR (0.32) TSHRFDPS
SCHEMBL29114517 0.77
SCHEMBL3482772 0.77
SCHEMBL8509107 0.75 TSHR (0.33) TSHR
SCHEMBL298404 0.75 TSHR (0.34) TSHRALDH1A1METAP1
SCHEMBL28959307 0.75 FDPS (0.41) FDPSMETAP1
SCHEMBL9869598 0.74
SCHEMBL21523303 0.73 KCNH2 (0.35) TSHRALDH1A1FDPSMETAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1067406-C Process for shortstopping emulsion polymerizations which does not generate nitrosamines ENICHEM ELASTOMERI S RL (IT) 2001-06-20 CN claimed
EP-0656371-B1 Process for shortstopping emulsion polymerizations which does not generate nitrosamines ENICHEM ELASTOMERS (IT) 1997-04-23 EP claimed
US-5504168-A USING ISOPROPYLHYDROXLAMINE ACETATE AND SODIUM POLYSULFIDE ENICHEM ELASTOMERI S.R.L. (IT) 1996-04-02 US claimed
CN-1110971-A Process for shortstopping emulsion polymerizations which does not generate nitrosamines ENICHEM ELASTOMERS (IT) 1995-11-01 CN claimed
EP-0656371-A2 Process for shortstopping emulsion polymerizations which does not generate nitrosamines ENICHEM ELASTOMERI S.r.l. (IT) 1995-06-07 EP claimed
US-3968101-A 8-Substituted cyclic nucleotides by free radical alkylation and acylation ICN PHARMACEUTICALS, INC. (US) 1976-07-06 US claimed
CN-1067406-C Process for shortstopping emulsion polymerizations which does not generate nitrosamines ENICHEM ELASTOMERI S RL (IT) 2001-06-20 CN disclosed
EP-0656371-B1 Process for shortstopping emulsion polymerizations which does not generate nitrosamines ENICHEM ELASTOMERS (IT) 1997-04-23 EP disclosed
US-5504168-A USING ISOPROPYLHYDROXLAMINE ACETATE AND SODIUM POLYSULFIDE ENICHEM ELASTOMERI S.R.L. (IT) 1996-04-02 US disclosed
CN-1110971-A Process for shortstopping emulsion polymerizations which does not generate nitrosamines ENICHEM ELASTOMERS (IT) 1995-11-01 CN disclosed
EP-0656371-A2 Process for shortstopping emulsion polymerizations which does not generate nitrosamines ENICHEM ELASTOMERI S.r.l. (IT) 1995-06-07 EP disclosed
EP-0063693-B1 PROCESS FOR THE MANUFACTURE OF EMULSIFIABLE POLYETHYLENE BY OXIDATION OF POLYETHYLENE IN A FLUIDISED-BED REACTOR BASF Aktiengesellschaft (DE) 1984-07-25 EP disclosed
US-4459388-A Preparation of emulsifiable polyethylene by oxidizing polyethylene in a fluidized bed reactor BASF AKTIENGESELLSCHAFT (DE) 1984-07-10 US disclosed
US-3968101-A 8-Substituted cyclic nucleotides by free radical alkylation and acylation ICN PHARMACEUTICALS, INC. (US) 1976-07-06 US disclosed