⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14486583 | 1.00 | — | — | |
| SCHEMBL3103340 | 0.79 | SLC1A2 (0.54) | — | |
| SCHEMBL12212883 | 0.77 | SLC1A2 (0.69) | — | |
| Oxalic Acid SCHEMBL27668327 | 0.75 | SLC1A2 (0.50) | — | |
| SCHEMBL28850932 | 0.75 | — | — | |
| SCHEMBL3261082 | 0.74 | TET2 (0.67) | — | |
| SCHEMBL6054264 | 0.74 | TET2 (0.67) | — | |
| SCHEMBL2437498 | 0.74 | — | — | |
| SCHEMBL21411550 | 0.73 | — | — | |
| SCHEMBL9487367 | 0.73 | SLC1A2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013004832-A1 | A NITRILE-METABOLISING ENZYME AND A PROCESS FOR PRODUCING AN ACID USING SAME | WATERFORD INSTITUTE OF TECHNOLOGY (IE) | 2013-01-10 | — | — | WO | claimed |
| WO-2013004834-A1 | A NITRILE-METABOLISING ENZYME AND A PROCESS FOR PRODUCING AN ACID USING SAME | WATERFORD INSTITUTE OF TECHNOLOGY (IE) | 2013-01-10 | — | — | WO | claimed |
| CN-119390757-A | Compound for resisting inflammation and osteoporosis and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2025-02-07 | — | — | CN | disclosed |
| US-11339193-B2 | CDP protein secretion inhibitors | KEZAR LIFE SCIENCES (US) | 2022-05-24 | — | — | US | disclosed |
| US-11339193-B2 | CDP protein secretion inhibitors | KEZAR LIFE SCIENCES (US) | 2022-05-24 | — | — | US | disclosed |
| CN-112513065-A | CDP protein secretion inhibitors | 科智生命科学公司 | 2021-03-16 | — | — | CN | disclosed |
| EP-3774850-A1 | CDP PROTEIN SECRETION INHIBITORS | Kezar Life Sciences (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20210017233-A1 | CDP PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2021-01-21 | — | — | US | disclosed |
| US-20210017233-A1 | CDP PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2021-01-21 | — | — | US | disclosed |
| WO-2019191527-A1 | CDP PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-10-03 | — | — | WO | disclosed |
| WO-2019191527-A1 | CDP PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-10-03 | — | — | WO | disclosed |
| CN-103014082-A | Biological preparation method of (R)-4-cyano-hydroxybutanoate | ENZYMEWORKS INC | 2013-04-03 | — | — | CN | disclosed |
| CN-103014082-A | Biological preparation method of (R)-4-cyano-hydroxybutanoate | ENZYMEWORKS INC | 2013-04-03 | — | — | CN | disclosed |
| WO-2013004835-A1 | ISONITRILE- AND NITRILE-METABOLISING ENZYMES AND A PROCESS FOR PRODUCING AMIDES AND ACIDS USING SAME | WATERFORD INSTITUTE OF TECHNOLOGY (IE) | 2013-01-10 | — | — | WO | disclosed |
| WO-2013004832-A1 | A NITRILE-METABOLISING ENZYME AND A PROCESS FOR PRODUCING AN ACID USING SAME | WATERFORD INSTITUTE OF TECHNOLOGY (IE) | 2013-01-10 | — | — | WO | disclosed |
| WO-2013004834-A1 | A NITRILE-METABOLISING ENZYME AND A PROCESS FOR PRODUCING AN ACID USING SAME | WATERFORD INSTITUTE OF TECHNOLOGY (IE) | 2013-01-10 | — | — | WO | disclosed |
| EP-0467132-B1 | 4-Substituted-2-hydroxybutanoates and a process for producing them | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5324852-A | Ring opening optically active a-hydroxybutyrolactone; esterification | CHISSO CORPORATION (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0467132-A2 | 4-Substituted-2-hydroxybutanoates and a process for producing them | CHISSO CORPORATION (JP) | 1992-01-22 | — | — | EP | disclosed |
| US-4048259-A | ADHESIVES | HENKEL & CIE GMBH (DT) | 1977-09-13 | — | — | US | disclosed |