SCHEMBL884664

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2063854	0.94	CCR8 (0.37)	CCR8ACHECPT1ACPT2SMN1; SMN2
	SCHEMBL884353	0.90	CCR8 (0.38)	KDM4ECCR8CPT1ACPT2SMN1; SMN2
	SCHEMBL2062570	0.90	CCR8 (0.39)	KDM4ECCR8ALDH1A1RECQLMAPT
	SCHEMBL2063373	0.89	CCR8 (0.37)	ROCK2CCR8CPT1ACPT2ALDH1A1
	SCHEMBL884829	0.88	FKBP1A (0.40)	ROCK2FKBP1AKDM4EACHECPT1A
	SCHEMBL2062020	0.88	KMT2A (0.41)	KDM4ECCR8ALDH1A1RECQLTP53
	SCHEMBL2062618	0.88	CCR8 (0.47)	KDM4ECCR8SMN1; SMN2ALDH1A1KMT2A
	SCHEMBL2063265	0.88	CCR8 (0.38)	KDM4ECCR8ALDH1A1RECQLTP53
	SCHEMBL2063134	0.86	CCR8 (0.37)	KDM4ECCR8ALDH1A1RECQLMAPT
	SCHEMBL10224836	0.85	CHRM3 (0.36)	CCR8SMN1; SMN2ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.