SCHEMBL8847019

SCHEMBL8847019

Clc1cc(Cl)c2ccccc2c1OCC1CO1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.49
ALDH1A1 P00352 4/20 0.47
TP53 P04637 3/20 0.47
TSHR P16473 3/20 0.47
HIF1A Q16665 3/20 0.47
CYP3A4 P08684 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GLA P06280 1/20 0.45
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
MAPT P10636 3/20 0.40
CYP1A2 P05177 3/20 0.40
CYP2C19 P33261 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HPGD P15428 2/20 0.36
PKM P14618 2/20 0.36
PPARG P37231 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
FGFR1 P11362 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19612356 0.88 ALDH1A1 (0.50) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL1715058 0.83 TDP1 (0.62) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL19612250 0.82 TDP1 (0.46) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL31560427 0.80 TDP1 (0.47) TDP1ALDH1A1TP53TSHRHIF1A
Methane SCHEMBL21633948 0.80 TDP1 (0.58) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL31120479 0.80 ALDH1A1 (0.44) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL19612307 0.78 ALDH1A1 (0.49) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL14655785 0.78 ALDH1A1 (0.56) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL23271831 0.77 ALDH1A1 (0.51) TDP1ALDH1A1TP53TSHRHIF1A
SCHEMBL17313693 0.77 ALDH1A1 (0.44) TDP1ALDH1A1TP53TSHRHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605937-B1 Antistatic resin composition DAISO CO LTD (JP) 1997-06-11 EP claimed
EP-0605937-A1 Antistatic resin composition DAISO CO., LTD. (JP) 1994-07-13 EP claimed
EP-0605937-B1 Antistatic resin composition DAISO CO LTD (JP) 1997-06-11 EP disclosed
US-5556916-A ACRYLONITRILE-BUTADIENE-STYRENE TERPOLYMER WITH POLYOXYETHYLENE GLYCOL POLYMER OR COPOLYMER ON RUBBER SUBSTRATE DAISO CO. LTD. (JP) 1996-09-17 US disclosed
EP-0605937-A1 Antistatic resin composition DAISO CO., LTD. (JP) 1994-07-13 EP disclosed