SCHEMBL8847152

SCHEMBL8847152

CC1=C(C#N)CNCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4060406 0.75
SCHEMBL14413443 0.73
SCHEMBL7332695 0.73
Potassium Ion SCHEMBL29475097 0.71 PNMT (0.36)
SCHEMBL1897635 0.69
SCHEMBL22909691 0.68 DRD2 (0.34)
Hydrochloric Acid SCHEMBL7050787 0.67 CHRM3 (0.34)
SCHEMBL21175175 0.66 PNMT (0.36)
SCHEMBL23706719 0.65
SCHEMBL7213132 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5668287-A Method for the preparation of 3-amino-2-chloro-4-methylpyridines BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1997-09-16 US claimed
EP-0551459-A4 1994-03-16 EP claimed
EP-0543000-A4 1994-03-16 EP claimed
EP-0551459-A1 METHOD FOR THE PREPARATION OF 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES. BOEHRINGER INGELHEIM PHARMA (US) 1993-07-21 EP claimed
EP-0543000-A1 NOVEL METHOD FOR PREPARING 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES. BOEHRINGER INGELHEIM PHARMA (US) 1993-05-26 EP claimed
US-5200522-A METHOD FOR PREPARING 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1993-04-06 US claimed
WO-1992022531-A1 METHOD FOR THE PREPARATION OF 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1992-12-23 WO claimed
WO-1992022532-A1 NOVEL METHOD FOR PREPARING 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1992-12-23 WO claimed
US-5668287-A Method for the preparation of 3-amino-2-chloro-4-methylpyridines BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1997-09-16 US disclosed
US-5200522-A METHOD FOR PREPARING 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1993-04-06 US disclosed
US-4833146-A BRAINS, BLOOD DISORDERS HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-23 US disclosed
EP-0255481-A1 Process for the photochemical stabilisation of a fibrous polyamide material and its mixtures with other fibres CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed