SCHEMBL8847192

SCHEMBL8847192

CCCCCCCCSC(=S)CO.CCCC[Sn]CCCC

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
HSD17B10 Q99714 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32
CES2 O00748 1/20 0.32
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
CYP2C9 P11712 1/20 0.32
BLM P54132 1/20 0.32
ACHE P22303 2/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9243483 1.00 LMNA (0.32) LMNAHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL9246948 0.89 LMNA (0.40) LMNAHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL9834737 0.88 LMNA (0.30) LMNA
SCHEMBL9622336 0.87 LMNA (0.36) LMNAHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL9581039 0.86 LMNA (0.33) LMNA
Ethylene Glycol SCHEMBL28747908 0.85 LMNA (0.42) LMNAHSD17B10ALDH1A1MEN1KMT2A
Ethylene Glycol SCHEMBL27667824 0.85 LMNA (0.42) LMNAHSD17B10ALDH1A1MEN1KMT2A
Ethylene Glycol SCHEMBL27430969 0.85 LMNA (0.42) LMNAHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL11436247 0.82 MAPT (0.32) HSD17B10MEN1KMT2ACES2GMNN
Ethylene Glycol SCHEMBL27328000 0.77 NOS3 (0.41) LMNAHSD17B10ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5688860-A GASKETS AND SEALS OF FLEXIBLE ELASTOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-18 US disclosed
EP-0648237-B1 POLYURETHANE/POLYUREA ELASTOMERS MINNESOTA MINING & MFG (US) 1997-11-05 EP disclosed
US-5621043-A Elastomeric sealants MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-04-15 US disclosed
WO-1996000754-A1 POLYURETHANE/UREA ELASTOMERIC SEALANTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-11 WO disclosed
EP-0666892-A1 CROSSLINKED POLYETHER POLYOL SEALANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-16 EP disclosed
EP-0452754-B1 Expandable non-sagging polyurethane compositions MILES INC (US) 1995-05-17 EP disclosed
EP-0648237-A1 POLYURETHANE/POLYUREA ELASTOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-19 EP disclosed
WO-1994010259-A1 CROSSLINKED POLYETHER POLYOL SEALANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-05-11 WO disclosed
US-5308657-A Protection of furniture edging MILES INC. (US) 1994-05-03 US disclosed
WO-1994000504-A1 POLYURETHANE/POLYUREA ELASTOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-01-06 WO disclosed
EP-0440934-A2 Sag resistant, unfilled, low viscosity urethane structural adhesive Bayer Corporation (US) 1991-08-14 EP disclosed
US-4994540-A Using amine terminated polyether as curing agent MOBAY CORPORATION (US) 1991-02-19 US disclosed
US-4954199-A REACTION PRODUCT OF POLYHYDROXY POLYETHER, DIAMINE OR TRIAMINE, ORGANIC ISOCYANATE MOBAY CORPORATION (US) 1990-09-04 US disclosed
EP-0343657-A1 Method for preparing chlorinated polyethylene suitable for blending with polyvinyl chloride to produce articles of manufacture having good impact resistance and clarity THE DOW CHEMICAL COMPANY (US) 1989-11-29 EP disclosed
EP-0248254-A2 Process for bonding laminates MOBAY CORPORATION (US) 1987-12-09 EP disclosed
US-4595445-A Adhesive is thermosetting reactive polyisocyanate-polyamine activated by heat or polar solvents BAYER AKTIENGESELLSCHAFT (DE) 1986-06-17 US disclosed
US-4546165-A Process for the production of stabilized polyisocyanates of retarded reactivity and their use in the production of polyurethanes BAYER AKTIENGESELLSCHAFT (DE) 1985-10-08 US disclosed
US-4483974-A POLYMERIZATION INHIGITION BY BLOCKING WITH AMINE, HYDRAZINE, OR HYDRAZIDE BAYER AKTIENGESELLSCHAFT (DE) 1984-11-20 US disclosed
US-4280940-A TRANSPARENT COMPOSITIONS OF GOOD VISCOSITY AND RESISTANCE TO LIGHT AND WEATHER HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-28 US disclosed
US-4113805-A DRY BLENDING HOECHST AKTIENGESELLSCHAFT (DE) 1978-09-12 US disclosed