Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.37 |
| ▸ | HMGCR | P04035 | 3/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847421 | 0.71 | FFAR1 (0.39) | EPHX2PTPN7HMGCRFFAR3HDAC3 | |
| SCHEMBL2396 | 0.71 | LMNA (0.42) | EPHX2PTPN7HMGCRFFAR3HDAC3 | |
| SCHEMBL21848002 | 0.70 | LMNA (0.36) | EPHX2PTPN7HMGCRFFAR3HDAC3 | |
| SCHEMBL4972079 | 0.69 | LMNA (0.53) | EPHX2PTPN7HMGCRFFAR3HDAC3 | |
| SCHEMBL3104209 | 0.69 | — | — | |
| SCHEMBL9823904 | 0.69 | LMNA (0.40) | EPHX2PTPN7HMGCRFFAR3HDAC3 | |
| SCHEMBL8847424 | 0.69 | PTPN7 (0.56) | EPHX2PTPN7HMGCRFFAR3HDAC3 | |
| SCHEMBL10163042 | 0.68 | EPHX2 (0.38) | EPHX2PTPN7HMGCRFFAR3HDAC3 | |
| Succinic Acid SCHEMBL3872448 | 0.67 | LMNA (0.48) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL577217 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778820-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1997-06-18 | — | — | EP | claimed |
| WO-1996006821-A1 | NEUROTROPHIC AND ANTIPROLIFERATIVE COMPOUNDS | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 1996-03-07 | — | — | WO | claimed |