SCHEMBL2396

SCHEMBL2396

O=C(O)C#CCCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
EGLN1 Q9GZT9 2/20 0.42
ALKBH5 Q6P6C2 1/20 0.42
SUCNR1 Q9BXA5 1/20 0.42
MAPK1 P28482 1/20 0.39
SLC13A3 Q8WWT9 1/20 0.39
OR51E2 Q9H255 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.38
EPHX2 P34913 1/20 0.37
PTPN7 P35236 5/20 0.37
HMGCR P04035 3/20 0.37
TSHR P16473 2/20 0.36
NFKB1 P19838 1/20 0.36
PMP22 Q01453 1/20 0.36
MAPT P10636 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9823904 0.97 LMNA (0.40) LMNAEGLN1ALKBH5SUCNR1MAPK1
SCHEMBL4970367 0.84 PTPN7 (0.50) LMNASLC22A6EPHX2PTPN7HMGCR
SCHEMBL4969753 0.82 PTPN7 (0.57) LMNASLC22A6EPHX2PTPN7HMGCR
SCHEMBL4972765 0.82 TBXAS1 (0.38) OR51E2
SCHEMBL4972079 0.82 LMNA (0.53) LMNAEGLN1ALKBH5SUCNR1MAPK1
Heptanoate SCHEMBL29243308 0.82 PTPN7 (0.67) OR51E2SLC22A6PTPN7HMGCRTSHR
SCHEMBL31520018 0.80 PTPN7 (0.61) LMNAEPHX2PTPN7HMGCRTSHR
SCHEMBL31520020 0.80 PTPN7 (0.61) LMNAEPHX2PTPN7HMGCRTSHR
SCHEMBL31520019 0.80 PTPN7 (0.61) LMNAEPHX2PTPN7HMGCRTSHR
SCHEMBL31520021 0.80 PTPN7 (0.61) LMNAEPHX2PTPN7HMGCRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13273 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748840-A1 IMIDAZO[1,2-A]PYRIDINE TYPE IRAK DEGRADATION AGENT AND USE THEREOF TAINUORUI (TIANJIN) BIOTECHNOLOGY CO., LTD (CN) 2026-05-27 EP claimed
EP-3365354-B1 PEPTIDES AND PEPTIDOMIMETICS IN COMBINATION WITH T CELL ACTIVATING AND/OR CHECKPOINT INHIBITING AGENTS FOR CANCER TREATMENT CANBAS CO LTD (JP) 2026-02-11 EP claimed
EP-4461734-B1 TYK2 INHIBITORS AND USES THEREOF ALUMIS INC (US) 2026-02-04 EP claimed
EP-4480953-B1 TYK2 INHIBITORS AND USES THEREOF ALUMIS INC (US) 2026-02-04 EP claimed
EP-4606434-A2 DEUTERATED DERIVATIVES OF RUXOLITINIB Sun Pharmaceutical Industries, Inc. (US) 2025-08-27 EP claimed
EP-3882249-B1 DEUTERATED DERIVATIVES OF RUXOLITINIB SUN PHARMACEUTICAL IND INC (US) 2025-05-14 EP claimed
CN-119818525-A Cytarabine amino acid ester composition and application thereof 沈阳信达泰康医药科技有限公司 2025-04-15 CN claimed
CN-119745904-A Application of paeoniflorin in preparation of medicine for treating tuberous sclerosis 澳门大学 2025-04-04 CN claimed
WO-2025039774-A1 IMIDAZO[1,2-A]PYRIDINE TYPE IRAK DEGRADATION AGENT AND USE THEREOF 泰诺瑞(天津)生物科技有限责任公司 2025-02-27 WO claimed
EP-4480953-A2 TYK2 INHIBITORS AND USES THEREOF Alumis Inc. (US) 2024-12-25 EP claimed
WO-2014207556-A1 PEPTIDES AND PEPTIDOMIMETICS IN COMBINATION USES AND TREATMENTS FOR CANCER PATIENT SUBPOPULATIONS CANBAS CO., LTD. (JP) 2014-12-31 WO claimed
US-8796226-B2 Depot systems comprising glatiramer or a pharmacologically acceptable salt thereof MAPI PHARMA LTD. (IL) 2014-08-05 US claimed
US-20110269790-A1 NOVEL THIENOPYRIDINES AS PHARMACOLOGICALLY ACTIVE AGENTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETIES ACT (ACT XXI OF 1860)) (IN) 2011-11-03 US claimed
EP-2373663-A1 THIENOPYRIDINES AS PHARMACOLOGICALLY ACTIVE AGENTS Council of Scientific & Industrial Research (IN) 2011-10-12 EP claimed
WO-2010076813-A1 THIENOPYRIDINES AS PHARMACOLOGICALLY ACTIVE AGENTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-07-08 WO claimed
WO-2008112167-A1 COMBINATION OF METFORMIN R-(+) LIPOATE AND ANTIHYPERTENSIVE AGENTS FOR THE TREATMENT OF DIABETIC HYPERGLYCEMIA AND DIABETIC COMPLICATIONS INDIGENE PHARMACEUTICALS INC. (US) 2008-09-18 WO claimed
US-20050220888-A1 Controlled release compositions and methods for using same SOUTHWEST RESEARCH INSTITUTE 2005-10-06 US claimed
US-20050054632-A1 Naphthyl compounds, intermediates, compositions, and methods of use BRYANT HENRY UHLMAN (US) 2005-03-10 US claimed
WO-2003105811-A2 CONTROLLED RELEASE COMPOSITIONS AND METHODS FOR USING SAME SOUTHWEST RESEARCH INSTITUTE (US) 2003-12-24 WO claimed
US-5288716-A Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis STEIGERWALD ARZNEIMITTELWERK GMBH (DE) 1994-02-22 US claimed