Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | BLM | P54132 | 4/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.55 |
| ▸ | APEX1 | P27695 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847942 | 0.98 | MAPT (0.56) | MAPTTDP1ADRB2KDM4EADRB1 | |
| SCHEMBL8848145 | 0.87 | TDP1 (0.60) | MAPTTDP1ADRB2KDM4EADRB1 | |
| SCHEMBL28315036 | 0.86 | TDP1 (0.44) | MAPTTDP1ADRB2KDM4EADRB1 | |
| SCHEMBL23920298 | 0.82 | HSD17B10 (0.46) | MAPTTDP1ADRB2KDM4EADRB1 | |
| SCHEMBL22607288 | 0.81 | ADRB2 (0.57) | TDP1ADRB2ADRB1TSHRCYP1A2 | |
| SCHEMBL9768151 | 0.81 | ADRB2 (0.63) | MAPTTDP1ADRB2KDM4EADRB1 | |
| SCHEMBL10727511 | 0.81 | KAT8 (0.58) | TDP1ADRB2KDM4EADRB1MEN1 | |
| SCHEMBL9768158 | 0.81 | ADRB2 (0.63) | MAPTTDP1ADRB2KDM4EADRB1 | |
| SCHEMBL1964126 | 0.81 | TDP1 (0.42) | MAPTTDP1ADRB2KDM4EADRB1 | |
| SCHEMBL29196543 | 0.80 | TDP1 (0.49) | MAPTTDP1ADRB2KDM4EADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610169-A | Pharmaceutical Composition containing slightly water-soluble drug | THE GREEN CROSS CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5462951-A | Dissolved in a polyoxyethylene sorbitan fatty acid ester and adsorbed onto a porosity inorganic substance | THE GREEN CROSS CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0448091-A2 | Pharmaceutical composition containing slightly water-soluble drug | THE GREEN CROSS CORPORATION (JP) | 1991-09-25 | — | — | EP | disclosed |