SCHEMBL9768158

SCHEMBL9768158

CCCCCCCCNCC(O)c1ccc(O)c(O)c1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 12/20 0.63
MAPT P10636 6/20 0.58
ADRB1 P08588 6/20 0.58
TDP1 Q9NUW8 6/20 0.58
KDM4E B2RXH2 6/20 0.58
HSD17B10 Q99714 5/20 0.58
DRD2 P14416 4/20 0.58
DRD3 P35462 4/20 0.58
ADRB3 P13945 4/20 0.58
TSHR P16473 4/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
MTOR P42345 3/20 0.58
MAPK1 P28482 3/20 0.58
DRD1 P21728 3/20 0.58
CYP1A2 P05177 3/20 0.58
HIF1A Q16665 3/20 0.58
ALDH1A1 P00352 2/20 0.58
CYP3A4 P08684 2/20 0.58
ADORA3 P0DMS8 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9768151 1.00 ADRB2 (0.63) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL13790391 0.98 ADRB2 (0.62) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL3220388 0.94 ADRB2 (0.61) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL9768153 0.94 ADRB2 (0.61) ADRB2MAPTADRB1TDP1KDM4E
Hydrochloric Acid SCHEMBL3227981 0.93 ADRB2 (0.62) ADRB2MAPTADRB1TDP1KDM4E
Hexoprenaline SCHEMBL32668781 0.92 ADRB2 (0.72) ADRB2MAPTADRB1TDP1KDM4E
Hexoprenaline SCHEMBL121449 0.92 ADRB2 (0.72) ADRB2MAPTADRB1TDP1KDM4E
Hexoprenaline SCHEMBL3500862 0.91 ADRB2 (0.70) ADRB2MAPTADRB1TDP1KDM4E
Hexoprenaline SCHEMBL1604446 0.91 ADRB2 (0.70) ADRB2MAPTADRB1TDP1KDM4E
SCHEMBL3503273 0.88 ADRB2 (0.65) ADRB2MAPTADRB1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5047592-A Selective hydrogenolysis process ETHYL CORPORATION (US) 1991-09-10 US disclosed