SCHEMBL8847713

SCHEMBL8847713

O=C(O)c1ccc(C(=O)/C=C/c2ccc(O)c(O)c2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.78
MAPT P10636 2/20 0.78
TERT O14746 1/20 0.78
CXCL12 P48061 2/20 0.74
XDH P47989 1/20 0.64
KDM4E B2RXH2 2/20 0.64
HSD17B10 Q99714 2/20 0.64
MEN1 O00255 1/20 0.64
HDAC3 O15379 1/20 0.64
CA12 O43570 1/20 0.64
AKR1B10 O60218 1/20 0.64
ALDH1A1 P00352 1/20 0.64
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64
LMNA P02545 1/20 0.64
TTR P02766 1/20 0.64
MMP1 P03956 1/20 0.64
APP P05067 1/20 0.64
GLA P06280 1/20 0.64
POLB P06746 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8847715 1.00 SNCA (0.78) SNCAMAPTTERTCXCL12XDH
SCHEMBL6377263 0.90 SNCA (0.73) SNCAMAPTTERTCXCL12XDH
SCHEMBL29036490 0.89 KDM4E (0.77) SNCAMAPTTERTCXCL12XDH
SCHEMBL8768038 0.88 XDH (0.81) SNCAMAPTTERTCXCL12XDH
SCHEMBL31233412 0.88 XDH (0.81) SNCAMAPTTERTCXCL12XDH
SCHEMBL25193897 0.88 XDH (0.81) SNCAMAPTTERTCXCL12XDH
SCHEMBL8768036 0.88 XDH (0.81) SNCAMAPTTERTCXCL12XDH
SCHEMBL30384507 0.88 MAPT (0.75) SNCAMAPTTERTCXCL12KDM4E
SCHEMBL25214104 0.88 MAPT (0.75) SNCAMAPTTERTCXCL12KDM4E
SCHEMBL30569484 0.88 MAPT (0.75) SNCAMAPTTERTCXCL12KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-5610169-A Pharmaceutical Composition containing slightly water-soluble drug THE GREEN CROSS CORPORATION (JP) 1997-03-11 US disclosed
US-5462951-A Dissolved in a polyoxyethylene sorbitan fatty acid ester and adsorbed onto a porosity inorganic substance THE GREEN CROSS CORPORATION (JP) 1995-10-31 US disclosed
EP-0448091-A2 Pharmaceutical composition containing slightly water-soluble drug THE GREEN CROSS CORPORATION (JP) 1991-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B SNCA 513/4885MAPT 3297/4885TERT 1096/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 SNCA 2137/4885MAPT 3512/4885TERT 878/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 SNCA 2137/4885MAPT 3512/4885TERT 878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.