Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848107 | 0.78 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL2441030 | 0.72 | MAPK1 (0.47) | ALDH1A1 | |
| SCHEMBL1736515 | 0.65 | — | — | |
| SCHEMBL2618716 | 0.64 | ALDH1A1 (0.63) | ALDH1A1DGKA | |
| SCHEMBL10901590 | 0.62 | ALDH1A1 (0.60) | ALDH1A1DGKA | |
| SCHEMBL17449766 | 0.62 | — | — | |
| SCHEMBL6115 | 0.62 | — | — | |
| Bis(Butyryloxymethyl) Succinate SCHEMBL18747588 | 0.62 | ALDH1A1 (0.60) | ALDH1A1DGKA | |
| Ethylene Glycol Dibutanoate SCHEMBL104207 | 0.62 | DGKA (0.65) | ALDH1A1DGKA | |
| SCHEMBL1866106 | 0.62 | ALDH1A1 (0.60) | ALDH1A1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614519-A | (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists | KARL THOMAE GMBH (DE) | 1997-03-25 | — | — | US | disclosed |
| US-5602127-A | ADMINISTERING TO TREAT HYPERTENSION | KARL THOMAE GMBH (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5594003-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-14 | — | — | US | disclosed |
| US-5591762-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0581166-A1 | Benzimidazoles, process for their preparation and their use as angiotensin-II antagonists | Dr. Karl Thomae GmbH (DE) | 1994-02-02 | — | — | EP | disclosed |