Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.77 |
| ▸ | MEN1 | O00255 | 9/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638932 | 1.00 | KMT2A (0.77) | KMT2AMEN1TDP1LMNAKDM4E | |
| SCHEMBL6638925 | 1.00 | KMT2A (0.77) | KMT2AMEN1TDP1LMNAKDM4E | |
| SCHEMBL6641811 | 0.87 | KMT2A (1.00) | KMT2AMEN1TDP1LMNAKDM4E | |
| SCHEMBL6641808 | 0.87 | KMT2A (1.00) | KMT2AMEN1TDP1LMNAKDM4E | |
| SCHEMBL6635021 | 0.85 | KMT2A (0.68) | KMT2AMEN1TDP1LMNAKDM4E | |
| SCHEMBL6635019 | 0.85 | KMT2A (0.68) | KMT2AMEN1TDP1LMNAKDM4E | |
| SCHEMBL6636069 | 0.84 | MEN1 (0.78) | KMT2AMEN1TDP1LMNAKDM4E | |
| SCHEMBL10027947 | 0.84 | MEN1 (0.78) | KMT2AMEN1TDP1LMNAKDM4E | |
| SCHEMBL6636064 | 0.84 | MEN1 (0.78) | KMT2AMEN1TDP1LMNAKDM4E | |
| SCHEMBL18804653 | 0.83 | KMT2A (0.72) | KMT2AMEN1TDP1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |