SCHEMBL6636069

SCHEMBL6636069

O=S(=O)(NN=Cc1ccccc1)c1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.78
KMT2A Q03164 6/20 0.78
ALDH1A1 P00352 8/20 0.71
TDP1 Q9NUW8 3/20 0.64
LMNA P02545 2/20 0.64
KDM4E B2RXH2 2/20 0.64
AGTR1 P30556 1/20 0.64
RECQL P46063 1/20 0.64
POLB P06746 2/20 0.63
GAA P10253 2/20 0.63
HTT P42858 4/20 0.62
SMN1; SMN2 Q16637 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
BCAT1 P54687 1/20 0.59
MAPT P10636 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10027947 1.00 MEN1 (0.78) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL6636064 1.00 MEN1 (0.78) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL714847 0.88 KMT2A (0.70) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL6635837 0.88 MEN1 (0.72) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL27596882 0.88 KMT2A (0.72) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL6638949 0.88 KMT2A (0.70) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL714848 0.88 KMT2A (0.70) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL6635840 0.88 MEN1 (0.72) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL18804653 0.88 KMT2A (0.72) MEN1KMT2AALDH1A1TDP1LMNA
SCHEMBL7001853 0.87 KMT2A (0.68) MEN1KMT2AALDH1A1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106977498-A Intracellular Fluorescence response flag DNA luminous point hits probe and preparation method and application 华南师范大学 2017-07-25 CN disclosed
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 EP disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed
US-4521542-A Arylsulphonyl hydrazones as blowing agents BAYER AKTIENGESELLSCHAFT (DE) 1985-06-04 US disclosed
EP-0129182-A1 Arylsulfonyl hydrazones as blowing agents BAYER AG (DE) 1984-12-27 EP disclosed
US-4473418-A OXYGEN-SUPPLYING SALT AS DISCONTINUOUS PHASE ORGANIC MEDIUM AS CONTINUOUS PHASE AECI LIMITED (ZA) 1984-09-25 US disclosed