SCHEMBL8848719

SCHEMBL8848719

NC(=O)/C(=N/O)c1ccccc1Oc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.54
GAA P10253 2/20 0.51
CYP2C19 P33261 1/20 0.51
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
MAPK1 P28482 2/20 0.48
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 5/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
HSD17B10 Q99714 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
HPGD P15428 2/20 0.42
HTT P42858 2/20 0.42
PARP10 Q53GL7 1/20 0.42
MAPK8 P45983 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8848694 1.00 CTNNB1 (0.65) CTNNB1SMN1; SMN2GAACYP2C19MEN1
SCHEMBL8848690 1.00 CTNNB1 (0.65) CTNNB1SMN1; SMN2GAACYP2C19MEN1
SCHEMBL8923090 0.87 CTNNB1 (0.59) CTNNB1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL8923077 0.87 CTNNB1 (0.59) CTNNB1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL5079797 0.83 CTNNB1 (0.59) CTNNB1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL1009759 0.83 CTNNB1 (0.59) CTNNB1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL8368445 0.83 CTNNB1 (0.59) CTNNB1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL8759289 0.81 CTNNB1 (0.53) CTNNB1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL8301449 0.81 CTNNB1 (0.53) CTNNB1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL2154335 0.80 CTNNB1 (0.51) CTNNB1SMN1; SMN2GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1051760-C (E) Process for producing (E) -alkoxyimino or hydroxyimino-acetamide compound SHIONOGI PHARMACEUTICAL K K (JP) 2000-04-26 CN disclosed
CN-1223248-A Process for producing (E)-alkoxyimino or hydroxyimino-acetamide compounds and intermediates therefor SHIONOGI & CO (JP) 1999-07-21 CN disclosed
EP-0596692-B1 A process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI & CO (JP) 1997-06-04 EP disclosed
US-5627284-A Process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI & CO., LTD. (JP) 1997-05-06 US disclosed
EP-0741125-A1 Benzyl compounds and process for producing same SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-11-06 EP disclosed
US-5442063-A Agricultural fungicides SHIONOGI & CO., LTD. (JP) 1995-08-15 US disclosed
CN-1103064-A (E) Process for producing (E) -alkoxyimino or hydroxyimino-acetamide compound and intermediate thereof SHIONOGI & CO (JP) 1995-05-31 CN disclosed
EP-0596692-A2 A process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-05-11 EP disclosed