SCHEMBL8923077

SCHEMBL8923077

O=C(O)/C(=N/O)c1ccccc1Oc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.49
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 6/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TSHR P16473 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 2/20 0.45
MAPK1 P28482 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
HTT P42858 2/20 0.43
MAPK8 P45983 1/20 0.43
GAA P10253 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8923090 1.00 CTNNB1 (0.59) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1
SCHEMBL8923108 0.89 LMNA (0.49) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1
SCHEMBL8923119 0.89 LMNA (0.49) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1
SCHEMBL8848694 0.87 CTNNB1 (0.65) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1
SCHEMBL8848690 0.87 CTNNB1 (0.65) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1
SCHEMBL8848719 0.87 CTNNB1 (0.65) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1
SCHEMBL8759289 0.84 CTNNB1 (0.53) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1
SCHEMBL8301449 0.84 CTNNB1 (0.53) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1
SCHEMBL2154375 0.83 CTNNB1 (0.51) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1
SCHEMBL2154374 0.83 CTNNB1 (0.51) CTNNB1SMN1; SMN2RAB9AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650539-A ALKYLATION, ESTERIFICATION, DEESTERIFICATION, AMIDATION, FUNGICIDES SHIONOGI & CO., LTD. (JP) 1997-07-22 US disclosed
US-5488159-A AMIDATION, METHYLATION, FUNGICIDE SHIONOGI & CO., LTD. (JP) 1996-01-30 US disclosed
US-5380913-A E-Isomers of 2-methoxyimino-N-methyl-2-phenoxyphenylacetamides and alkyl 2-methoxyimino-2-phenoxyphenylacetates produced by reacting Z-isomers with hydrogen chloride or hydrochloric, sulfuric or toluenesulfonic acid in methyl, ethyl or butyl alc SHIONOGI & CO., LTD. (JP) 1995-01-10 US disclosed
EP-0468775-B1 Process for producing methoxyiminoacetamide compounds and intermediates SHIONOGI & CO (JP) 1994-12-14 EP disclosed
EP-0606924-A1 Process for producing E-isomers of methoxyminoacetamide compounds SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-07-20 EP disclosed
EP-0605392-A1 Process for producing methoxyminoacetamide compounds SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-07-06 EP disclosed
US-5183921-A Agricultural fungicides SHIONOGI & CO., LTD. (JP) 1993-02-02 US disclosed
EP-0468775-A1 Process for producing methoxyiminoacetamide compounds and intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1992-01-29 EP disclosed