Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848545 | 0.89 | RAB9A (0.52) | RAB9ANPC1L3MBTL1HDAC6LMNA | |
| SCHEMBL8848722 | 0.89 | RAB9A (0.65) | RAB9ANPC1L3MBTL1HDAC6LMNA | |
| SCHEMBL8848405 | 0.88 | NPC1 (0.64) | RAB9ANPC1L3MBTL1HDAC6LMNA | |
| SCHEMBL8848574 | 0.88 | HDAC6 (0.64) | RAB9ANPC1L3MBTL1HDAC6LMNA | |
| SCHEMBL8848839 | 0.87 | HDAC6 (0.60) | RAB9ANPC1L3MBTL1HDAC6LMNA | |
| SCHEMBL8848554 | 0.87 | RAB9A (0.50) | RAB9ANPC1L3MBTL1HDAC6LMNA | |
| SCHEMBL8848678 | 0.87 | RAB9A (0.53) | RAB9ANPC1L3MBTL1HDAC6LMNA | |
| SCHEMBL8848771 | 0.86 | RAB9A (0.52) | RAB9ANPC1L3MBTL1HDAC6LMNA | |
| SCHEMBL8848821 | 0.86 | HDAC6 (0.54) | RAB9ANPC1L3MBTL1HDAC6LMNA | |
| SCHEMBL8848549 | 0.85 | TP53 (0.52) | RAB9ANPC1L3MBTL1HDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | claimed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | claimed |
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |